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Help me with depression

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Patent Abuse or Genius? Is Kyle Bass Abusing the Patent System? Yesterday the Wall Street Journal published an article explaining the novel strategy of Kyle Bass, head of Hayman Capital Management, to make money by invalidating patents. Bass, who has teamed up with Erich Spangenberg, has filed several petitions for help me with inter partes review (IPR) at the United States Patent and Trademark Office (USPTO) asking the Patent Trial and Appeal Board (PTAB) to invalidate patent claims covering drugs. Bertolt Epische! After filing the IPR Bass then either shorts the stock of the help, company owning the patent, or he buys shares in writing formats, companies that would be benefited by the patent claims becoming invalidated. Help Me With Depression! What Bass is doing is alternatively characterized as creative and corporate strategy case studies essays brilliant, or evil and depression abusive. Once upon a time it was widely believed that post grant challenges would only be a problem for patent owners in the high-tech sector. Increasingly, however, pharmaceutical and corporate case studies biotechnology companies are finding that their patents are coming under fire, which is alarming given that these companies have relatively few patents covering the commercialized product. If the Bass challenge is successful there will be many more that follow due to help me with, the heavy reliance on patents to protect the extremely expensive research and formats development required to take pharmaceuticals and biosimilars to market. Indeed, if Bass is successful it could be catastrophic for the industry.

Regardless of whether you believe Bass is doing a public service, or he is engaged in help me with depression, an unforeseen abuse of process, an important question remains: Is Bass able to use IPR to challenge patent claims in ado essay much nothing, this way? Unfortunately, the answer is complicated due to the fact that the statute seems to me with, suggest one answer, while the legislative history suggests a different answer. Post Grant Review at the USPTO. The history of post grant review at the USPTO is relatively short. Starting on September 16, 2012, on the first anniversary of the corporate strategy studies, signing of the America Invents Act (AIA), the PTAB was born. The jurisdiction of the PTAB is greatly expanded compared to the previous Board of depression Patent Appeals and field track Interferences (BPAI). Most specifically, the PTAB conducts trials within the Patent Office. These trials are required by help depression, the new procedures ushered in by the AIA, namely Inter Partes Review (IPR), Post-Grant Review (PGR) and Covered Business Method (CBM) Review. Jane! These three new varieties of patent challenge allow a petitioner to challenge the propriety of one or more patent claims once they have been granted by the Patent Office. The challenges being brought by Bass are IPRs. Me With! In an IPR the brecht essay epische theater, petitioner may request to cancel as unpatentable one or more claims of a patent only on a ground that could be raised under 35 U.S.C.

102 or 103 and only on help me with, the basis of prior art consisting of patents or printed publications. See 35 U.S.C. 311(b). The contest between the petitioner and patent owner is played out in article, an administrative trial in front of help me with depression a panel of the much, PTAB. Help Me With! The PTAB will not institute an epische IPR unless there is a reasonable likelihood that the petitioner would prevail with respect to at least one of the claims challenged in me with, the petition. The determination by the Director whether to institute an inter partes review under 35 U.S.C. 314 is final and nonappealable.

See 35 U.S.C. 314(d). According to the statute, “[a] person who is not the owner of a patent may file a petition to epische theater, institute an inter partes review of the patent.” 35 U.S.C. 311(a). Similarly, with PGR “[a] person who is not the owner of a patent may file with the Office a petition to me with, institute a post-grant review of the corporate case, patent.” 35 U.S.C. 321(a). However, when it comes to CBM things are quite a bit different: “[a] person may not file a petition for a transitional proceeding with respect to a covered business method patent unless the person or the person’s real party in help me with, interest or privy has been sued for infringement of the patent or has been charged with infringement under that patent.” AIA § 18 (a)(1)(B). As you can see, in order to challenge a patent using CBM the essay theater, petitioner must be a defendant in a patent infringement lawsuit, or have been charged with infringement. No such similar requirement exists for either IPR or PGR. Me With! This is corporate, why Bass has a legitimate reason to believe that he can challenge patents despite having no direct interest in the patent either as an alleged infringer, licensee or prospective licensee. Despite the fact that the statute on help me with depression, its face seems to strategy studies essays, allow any petitioner to file an IPR, it still feels wrong to many in the industry that a wealthy businessman should be able to reap financial rewards for a situation he creates.

This is no doubt reinforced by familiarity with post grant procedures at help me with the USPTO and paper why they were created in help depression, the first place. Time and time again throughout the legislative history post grant proceedings were explained as being a faster, low-cost alternative to college writing, litigating validity disputes in Federal District Court. That being the case, it would seem extremely odd that any petitioner could bring a post grant challenge to a patent when that petitioner would not have standing to sue to depression, invalidate the patent in case studies, Federal District Court. Help Me With! Make no mistake about it – Kyle Bass would not be able to take his challenge to Federal District Court. He would have no standing to bring a Declaratory Judgment Action. There is no case or controversy. Essays! So why then would he have standing to bring a post grant challenge?

Patent reform efforts that ultimately culminated in the AIA were underway for at help me with depression least five years prior to enactment of the legislation. In one earlier round of reform attempts, on April 18, 2007, Congressman Howard Berman speaking on brecht essay theater, the introduction of the Patent Reform Act of 2007, explained that the post grant procedures in the legislation were to “provide meaningful, low-cost alternatives to help, litigation for challenging the patent validity…” Berman would go on to say: “The post-grant procedure is college paper formats, designed to help me with, allow parties to challenge a granted patent through a expeditious and less costly alternative to litigation. Many have expressed concerns about the possibility of harassment of patent owners who want to assume quiet title over their invention. In an effort to address those concerns, the bill prohibits multiple bites at the apple by restricting the essays jane, cancellation petitioner to help, opt for only one window one time. The bill also requires that the Director prescribe regulations for bertolt essay theater sanctions for help me with abuse of process or harassment.” This theme is constantly repeated throughout the legislative history. Brecht Essay Epische Theater! Post grant procedures were designed to be an alternative to litigation, and Congress was well aware of at least some potential abuses of the new procedures. Help! The intent was to give those with a justiciable grievance a cheaper, faster forum in which to challenge a patent. Likewise, the procedures were designed to the greatest extent possible to prevent abuse of process and/or harassment. Article Field Sport! The legislative history is silent with respect to the type of challenge Bass is bringing, although it stretches the imagination to believe that Congress intended to help me with, allow pharmaceutical companies to be subjected to a challenge by an individual or entity that would not have standing to sue in Federal District Court. But Congressman Berman was not the only one to make these same assertions, nor were they only made with respect to the Patent Reform Act of 2007.

One of the three goals of the Patent Reform Act of 2007 was “to improve and clarify several aspects of patent litigation, including the creation of a less expensive, more expeditious administrative alternative to litigating patent validity issues,” explained Senator Patrick Leahy (D-VT) on January 24, 2008. “The time has come to eliminate the inter partes reexamination system and replace it with a new post-grant review system at the USPTO that will give third parties a quick, inexpensive, and reliable alternative to district court litigation to resolve questions of patent validity.” Similarly, in a report from the minority relating to post grant review procedures contained within the Patent Reform Act of 2007, Senators Tom Coburn (R-OK), Charles Grassley (R-IA), Jon Kyl (R-AZ) and magee questions Sam Brownback (R-KS), explained that post grant review procedures “should be timely and streamlined and me with depression should take issues off the table that cannot be resurrected in subsequent litigation, providing a cost effective alternative to litigation. To protect patent holders from maniac magee essay harassment and abuse by me with depression, a competitor or infringer, the system must be narrowly crafted with appropriate safeguards.” Fast forward to 2011. On the Senate floor during the patent reform debate on February 28, 2011, Senator Orrin Hatch (R-UT) explained: “The bill will also establish another means to administratively challenge the validity of a patent at the U.S. Patent and Trademark Office, USPTO— creating a cost-effective alternative to formal litigation, which will further enhance our patent system.” Senator Grassley similarly explained that the pending bill would “provide faster, less costly alternatives to civil litigation to challenge patents.” Senator Leahy also explained during the debate that post grant procedures would “offer productive alternatives to costly and complex litigation.” On March 7, 2011, Senator Leahy would again echo his previous comments, saying the bill would “streamline the current ‘inter partes’ system so that it will be a more efficient alternative to litigation.” Similarly, Senator Mark Udall (D-CO) explained that post grant proceedings “are intended to serve as a less-expensive alternative to courtroom litigation and provide additional access to the expertise of the Patent Office on questions of maniac magee essay questions patentability.”

Senator Jeff Sessions (R-AL), also spoke in some detail about the help depression, measures Congress was taking to help ensure that post grant proceedings did not become abusive. Sessions explained: “The bill also includes many protections that were long sought by inventors and patent owners. Essay Theater! It preserves estoppel against relitigating in court those issues that an inter partes challenger reasonably could have raised in his administrative challenge. It imposes time limits on starting an inter partes or post-grant review when litigation is pending. And it imposes a one-year time limit on the duration of these proceedings. Help Depression! All of these reforms will help to ensure that post-grant review operates fairly and is not used for purposes of harassment or delay.” In the House of Representatives, on June 22, 2011, the primary architect of reform in the House, Congressman Lamar Smith (R-TX) repeatedly explained that the purpose of allowing post grant challenges to issued patents was to provide a low cost alternative to invalidate patent claims. At one point during the college, day Smith explained that post grant challenges “would create a cheap and depression speedy alternative to litigation— allowing parties to resolve these disputes rather than spend millions of dollars that litigation now costs.

In the process, the proceeding would also prevent nuisance or extortion litigation settlements.” Even the bertolt, Obama Administration understood post grant proceedings to be for the purpose of creating an alternative to litigation in Federal District Court. Help! Then Commerce Secretary Gary Locke explained that a post grant challenge “decreases the likelihood of expensive litigation because it creates a less costly, in-house administrative alternative to paper formats, review patent validity claims.” Given the universal agreement that the purpose for creating new post grant challenges was to create a low-cost alternative to litigation to determine the validity of patent claims it is help me with, difficult to understand why the Bass challenge should be allowed to move forward. Furthermore, given the concern about corporate essays, extortion litigation settlements, abusive challenges and harassment of depression patent owners, it seems unlikely that Congress would be supportive of the type of challenge that Bass is pursuing using IPRs. Of course, if Congress wanted to limit IPR and PGR to petitioners who had a vested interest in the outcome they could have done so, as they did do with CBM challenges. It will be interesting to see what happens with the Bass petitions, and even more interesting to see whether Congress steps in to bail out the epische theater, pharmaceutical industry. After all, it was the pharmaceutical lobby that drafted the AIA in the first place. Help! How ironic that the AIA could bring the industry to maniac magee, its knees. * For a compilation of documents that make up the legislative history please see Comprehensive Legislative History of the Leahy-Smith America Invents Act , Compiled, Edited, And Abridged by Patrick A. Doody, Pillsbury Winthrop Shaw Pittman. Gene Quinn is a Patent Attorney and Editor and founder of

Gene is also a principal lecturer in the PLI Patent Bar Review Course and an attorney with Widerman Malek. Gene’s specialty is in the area of strategic patent consulting, patent application drafting and patent prosecution. He consults with attorneys facing peculiar procedural issues at depression the Patent Office, advises investors and executives on patent law changes and pending litigation matters, and ado essay much works with start-up businesses throughout the United States and around the world, primarily dealing with software and help computer related innovations. College Paper Writing Formats! Gene is admitted to practice law in New Hampshire, is a Registered Patent Attorney and is also admitted to practice before the United States Court of Appeals for the Federal Circuit. CLICK HERE to send Gene a message. Warning Disclaimer : The pages, articles and comments on do not constitute legal advice, nor do they create any attorney-client relationship. The articles published express the personal opinion and views of the author and should not be attributed to the author’s employer, clients or the me with depression, sponsors of Read more. There are currently 37 Comments comments. The problem for Pharma is only in respect of invalid patents they hold.

The valid patents will remain intact. So one way of avoiding this problem and ensuring they have robust stock values is to make sure they only article field proposal sport track, try and monopolize patentable inventions. You miss the help depression, point. When an IPR challenge is brought patent owners need to be prepared to spend about $1 million (or more) to defend a patent already lawfully obtained. Further, there is no reason to believe that IPR was intended to allow for this type of strategy. Further, your view of a patent as a monopoly misses the point as well. A patent only provides the opportunity for monopoly profits for a very short time. A patent is not a monopoly, nor does it guarantee a monopoly.

This is bertolt essay, a critical distinction because to have monopoly power you need to have something that other people are willing to pay for and acquire. These valuable inventions were not the help me with depression, type of inventions that anyone thought would be subject to post grant challenge. Post grant challenges were created to deal with low quality patents in the tech sector, not pharmaceuticals. Indeed, no industry actor would ever consider challenging a pharmaceutical patent in essays, an IPR when there are significant advantages to challenging in Federal District Court under Hatch-Waxman. So it seems pretty clear to me that the Bass action here is the result of an help me with unintended consequence of the AIA. I think this is further evidence that no one was really thinking very much or well when they improved the patent system. Field Sport Thesis! Standing has been a requirement in article iii litigation since the beginning of help depression time.

Really, the essays on calamity, improvements have only depression, weakened inventor’s rights and converted a property system into a litigation/tort system stacked against inventors and firms who invest in research and development. They have substituted 1000 page requests for motions with 50 page limits, given disinterested individuals the right to threaten property rights of innovators, and strategy introduced massive uncertainty into the field of innovation. And yet we will see another wave of “improvements” soon. Perhaps better regulations could be promulgated that would institute a standing requirement. Perhaps the help, Office should also consider whether it should respect the decisions it has already made in issuing the patent. While the statute creates a presumption of validity in the courts, shouldn’t it be logical that the Office should be bound by its own factual findings, at least to on calamity, some extent? If the Office isn’t so inclined, doesn’t it really decrease faith in its own operations? The real mystery to me is why this ever took place. I may be wrong, but most of the invalidation arguments are obviousness arguments. In a world with all of the information technology available so readily, the fact that an obviousness argument can be collaged doesn’t seem impressive to me, nor fatal to the merits of an invention.

The fact that often the challenges are based upon several references, strikes me as an indication that we are focusing on the wrong things. Depression! We really need a property system that will encourage creativity in effective business relationships and licensing more than we need fanciful litigation. I can assure you I am not missing any of the points and I like the article. These procedures may be a new thing for the US but outside of the US we have had patent opposition procedures for years that have been instigated by numerous interested third parties for 101 reasons one of which I am sure is making money on stock fluctuations. The thing is strategy essays, that a reasonable number of US patents that have been “lawfully” obtained are not actually “lawfully” valid. Big Pharma are just as prone to push the boundaries on this as anyone else. There is so called “abuse” of the patent system from all quarters. This “new” US phenomena may get some to me with depression, up their game. I see US patents across sectors that are of suspect validity every week.

Just because Pharma spends big on RD and innovation does not mean they are entitled to on calamity jane, invalid patents. They are no more worthy than any other sector. We all know that Pharma play games with the patent system to extend their monopoly periods. I think the monopoly issue is just semantics anyway. There is significant advantage for post grant challenge over the courts.

The main one being the quality of assessment and help me with another is the costs. In Europe for example most would prefer an maniac opposition division that at me with least understands novelty as opposed to a Judge that may not and nothing a quality low cost outcome. The US system at $1 million or more is just a bad joke from a relative point of help me with depression view on costs but it is cheaper than the unpredictable US courts. I know there may have been certain motivations for this new US system derived from a desire to “clean up” tech sector patents (which I support entirely), but I see no reason why it should not be used to “clean up” the patents in all sectors and Pharma is college paper, as good as any. I suppose Pharma is an obvious target for this “new” business model as they have fewer patents that are more critical. If you look at the tech sector post Alice 80% of their patents are complete trash…..but what about their stock values? Hardly a flutter.

That tells you something. I agree that this Hedge fund activity does not appear to have been envisaged at least by those who proposed the system in the US, but it’s not that surprising to those outside of the US. It may have been unintended but you could actually see it coming a mile off! What Kyle Bass is doing here just proves (again) that Congress failed to think through all the potential consequences of these IPR proceedings when enacting the AIA (Abominable Inane Act) legislation. And HR 9 has the same potential to cause such “unintended consequences.” I would make one further point on “unintended” consequences. We see that occur all the time when the courts make decisions that are clearly not supported by the actual legislation or the spirit of the legislation. These Judges just make the law up as they go along. Business method patents are a prime example.

These abominations and help me with depression associated bad behaviour are the root cause of much of the rapid and ill thought out legislation we are wrestling with in the US. There is plenty being caught in essays, the crossfire. This is depression, rather intriguing. When Erich Spangenberg was a big bad patent troll, he was using patent law to find infringers and make money. Now, he’s finding bad patents (at least from his perspective) and attempting to invalidate them. He’s only going after publicly traded companies which should have vetted their patents long ago. I suspect you’ll be seeing challenges to patents like, US 7,769,600, Disease Management System and Method — Allowing a patient access to an automated process for managing a specific health problem called a disease. A low quality patent is a low quality patent. On Calamity! Invalidating pharma and biotech will require a deeper bench of help experts on article sport thesis track, both sides and isn’t going after businesses who want to let their customers read their email via wifi while sipping their morning coffee. One thing that I have not seen much reflection on me with, is the fact that inter partes reviews replaced the inter partes reexamination system, which also did not have a standing requirement.

Would Bass’ business model have worked just as well under that system, or are there special features of the essays on calamity, current IPR system that are of particular concern? Sorry, but if you are trying to say that business method patents are a creation of the judiciary you are sadly mistaken. Read the Patent Statute and you will notice that business methods are specifically mentioned in the text. Furthermore, all kinds of business methods were patentable long before State Street. Not surprisingly, I agree with you completely.

The problem with patent legislation is that it does nothing to actually improve the system. The AIA just rearranged the me with, chairs on the deck to create a different set of maniac magee laws. It didn’t harmonize our laws with other countries. We are just different in other ways than we once were. This is also a major problem with the Innovation Act. It seems that Congress wants to play whack-a-mole without any kind of thought about whether this improves the system or even addresses the problem they intend to help me with depression, solve. For example, fee shifting will not solve the problem they think they observe. To get fees you have to actually prevail, which means going all the way to maniac magee, the end. But we know that the me with depression, big companies settle with patent trolls for nuisance value. The only time they fight to maniac magee essay, the end is with valuable commercial innovations.

Gene — should Bass be successful in his IPR effort(s), would he have Article III standing assuming the losing pharma/bio company appealed? Yes I am aware of the help depression, history. I was of ado essay much course referring to computer or internet implemented inventions and post State Street. Someone recently pointed out the clear increase in me with, patenting rates post State Street. Essays On Calamity! It’s clearly part of the help depression, problem hence the need to corporate strategy studies essays, deal with junk tech patents. The “unintended consequences” of State Street are “real” Patent Trolls not NPEs and the current attacks on invention and innovation. I think the problem is more complex than that. Me With Depression! The shift to this area of thinking has infested all areas of innovation and lead to some amusing outcomes. One example is US 8,865,100. The other is US Supreme Court and “abstract ideas”.

The only paper formats, problem I have with the US IPR area is the ridiculous costs. We can achieve a usually quality result after an Appeal process in help me with depression, Europe for a fraction of these costs. The parties get justice as does the public when bad patents are dead. So these people are engaged with a stock play. Big deal. Parties have been using IP related issues for ado essay nothing decades to me with, impact company values and college formats make money. One upside of help me with depression this activity is decluttering the top end of Pharma and increasing the article field sport track, drive for new technologies and acquisition from start-ups and dare I say it NPEs. I wonder if Mr Bass and Mr Spangenberg have a bob or two invested in that area? #128521;

Here’s a thought….perhaps we should label Kyle Bass a “reverse patent troll”, draw up an me with depression new scary image of sport thesis what would look like and bring a new round of help depression legislation with massive Google-style lobbying efforts to nothing, Congress to combat this out of control “problem”. All one needs to do is convince Goidlatte and Issa that you are a champion for innovation, and visit the help, White House 230 times over the next few yearS #128578; Is anyone laughing yet about the brecht essay, current HR9 situation and me with all of it’s “unintended consequences”? Wonder if any of it’s backers give a hoot about this issue? I would bet not. Jeez, looks like true innovation in America is under attack from essays on calamity all sides, even if for sport, by those with tremendous influence and financial resources….and only their own sole interests at help depression heart. Maybe the corporate studies essays, Wall Street Journel (besides you Gene) is becoming the mainstream paper of record on this brazen daylight heist of America’s essential new business incubating process. Let’s hope folks in Washington are reading and paying attention. with all due respect – looking from the lens of purpose or intent may be informative. seeking to invalidate ip for the purpose of profit by speculation primarily serves a few people, speculators. it also seems to help me with depression, undermine the system that encourages entities to take risks in the process of expanding mankind’s understanding by rewarding them with exclusivity. speculation just produces more capital – the federal reserve has invented the mean to create endless capital – that at the end of the day seems to be hurting many people… i am in favor of ensuring a better life by encouraging and protecting people and entities that focus on making life better by finding new and novel solutions and college paper writing formats not just by help depression, making more money by speculation.

i am very much a capitalist, but believe without purpose and service to others we are lost. hope this is helpful. big lather inventor. Same sad, old story: Money men vs. idea men. Money men win. same story, new day with more understanding. we are learning that capital creation is endless, but good ideas are harder to come by much nothing, – so as we evolve, good ideas need to triumph over endless bad capital creation… or we all perish, surrounded by piles of worthless money:) “Given the universal agreement that the me with depression, purpose for creating new post grant challenges was to create a low-cost alternative to litigation to ado essay much nothing, determine the validity of patent claims it is help me with depression, difficult to understand why the Bass challenge should be allowed to move forward.” I have a hard time agreeing with this statement. Article Field Proposal Thesis Track! Nothing about Mr. Bass’s action are contradictory to the purpose of help me with depression creating a low-cost alternative for determining validity.

Even if each IPR/PGR costs $1 million to litigate (which is on the very high end of the paper writing, ones I have worked on), that is still cheaper than litigation for both the help, challenger and the patent holder. If anything, the statement made in the conclusion is inapposite to the issue of maniac questions cost. Although I generally do not approve of the help me with, business model of college paper writing NPEs/trolls, I am opposed to the sweeping legislation that is pending in Congress. Similarly, I do not like the idea of having Congress “fix” the issue of hedge funds challenging patents of questionable validity. If anything, I view invalid patents to be a market inefficiency to the extent that they create barriers to entry (real or perceived) for competitors. Depression! Mr. Essays! Bass is exploiting that market inefficiency to make money. Help! That sounds like an case entrepreneurial approach that most capitalists could get behind. This article seems to suggest that IPRs and PGRs should be modified to change the standing requirement to prevent challenges from parties like hedge funds.

I see a similarity between this idea and efforts to curb patent trolls. Me With Depression! With respect to the latter, observers often say that we could cure the problem of patent trolls by preventing a party from paper formats suing another unless it is actually practicing its patent. I abhor this idea, and I would guess that many of the commenters on this blog feel the same way. But how is me with depression, that approach any different from maniac magee questions what is suggested with respect to me with depression, preventing a hedge fund from essay epische challenging a patent’s validity? At the end of the day, I think the me with depression, market can solve the problem posed by Mr. Bass all by itself. If a publicly-owned corporation wants to avoid exposure to challenges like this, they should give more careful consideration to the patent claims they prosecute. They can pursue a range of proposal claims, some more broad and others more narrow. By obtaining a large number of claims of varying scope, it makes challenges by third parties more difficult and less attractive to people like Mr. Bass.

“. . . Help Depression! it still feels wrong to many in the industry that a wealthy businessman should be able to reap financial rewards for a situation he creates.” This is another statement that seems incorrect to me. How has Bass created the situation? He did not prosecute the patents, not did he examine/allow the claims having specious validity. He did not create the IPR/PGR processes. I hate that I am defending Bass’s actions, but I have yet to see a criticism of his tactics that makes sense. If the patent is valid, then I trust that the patent owners will be vindicated either at ado essay nothing the PTAB or the Federal Circuit. with all due respect, mr. bass and other extorters of unearned rents may not care if they win or loose in help depression, the patent review process as long as they extract more profit than the cost of the hit and run process – that is formats, what really needs to be debated… as well as the collateral damage to the spirit of innovation that must now fear the help depression, bully of too big to fail money… big lather inventor.

To be fair, Bass’s scheme relies on targeting publicly-held companies. The patents of small businesses (i.e., loosely-held corporations and privately owned companies) are not going to be at risk here because there is little money in much, it. I suppose he could challenge a patent of a small business if doing so would raise the stock of help depression a publicly-held competitor, but I believe those situations are uncommon. Considering the fact that large corporations are probably the most common target of his challenges, I think that these parties have the ability to defend their patents, so I am not sure how much “bullying” is taking place. And they certainly can find creative ways to make these types of challenges less attractive, such as by on calamity jane, obtaining a large number of claims with different scope (as I mentioned above). Help Depression! Certainly there is a calculus of balancing the strategy essays, potential profit against the cost, but I have a hard time believing that the help me with depression, stock will fluctuate very much just due to the fact that someone files an article field proposal sport thesis track IPR challenge. Beside, if the challenge has little merit, the patent owner can seek sanctions against the challenger. “Loosely-held” should be “closely-held” in help depression, the comment above. Sorry for college formats the typo. Post grant trials instituted by the AIA did not really provide a “new” avenue of attack on patents, rather they are essentially just revised versions of previously available reexamination procedures (ex parte (which is still available) and more closely inter partes reexam). The scheme being relied upon by help me with depression, Bass could have been readily implemented for proposal track over a decade prior to enactment of the AIA.

However (and this is a BIG however), the former reexamination proceedings tended to me with depression, be patent owner friendly and very slow – making implementation of ado essay Bass’s scheme much more difficult and risky. Accordingly, it is only the statistical success of invalidating patents in trials in front of the help me with, AIA that make IPRs or CBMs an attractive avenue for use in “schemes” such as the one discussed here. We are already seeing a shift in sport thesis, the statistics of help success in invalidating patents in front of the PTAB and I believe (hope) it will continue to become more balanced in the future. In the end, I tend to agree that this is an abuse of the system, but it is not a new avenue for abuse – just a more friendly one (at least currently). From this side of the pond, the problems seem to be procedural in corporate essays, nature. The theory of help depression allowing challenges by persons without locus standi is magee essay, good. The issue is that there is me with depression, no penalty for over-lawyering. The system will shake out once the rules genuinely allow a fair defence to be launched, and the PTAB proves it issues high quality judgments. Patents in Europe have high value and are challengeable by any person in college paper writing, EPO opposition procedures, but the costs are 5% because the EPO does not encourage parties to instruct the level of lawyering that seems commonplace in USA. Let the hedge funds play in our world, their main interest is their own pockets, but the help, general public benefits from the register being cleared of patents that are invalid.

“That being the field proposal sport, case, it would seem extremely odd that any petitioner could bring a post grant challenge to depression, a patent when that petitioner would not have standing to sue to invalidate the patent in Federal District Court. ” How is the IPR Process any different than prior reexamination (post grant) procedures? In fact ex parte can be filed by anyone anonymously. I see absolutely no prohibition on this, and in fact the CBM procedure shows you Congress knew when it wanted to impose restrictions, and when it did not. I think we are going to see more of Bass and bertolt epische theater others because the language contains no restrictions. Congress was specifically trying to fix a problem with inter partes reexamination. It was not viewed as an adequate or suitable alternative to district court litigation.

So that is why they say over help depression and over again in the legislative history that they wanted to scrap inter partes reexamination in favor of something that would be a meaningful (and used) alternative to essays on calamity, litigation. I think without a legislative fix it will be extremely difficult to help me with, prevent this type of use. Writing Formats! The statute is help depression, pretty clear, and as you point out bertolt brecht essay epische they know how to help me with depression, require standing because they did that with CBM. With the statute being so clear you probably never get to the legislative history for guidance. The real problem with interpartes was that it was not resulting in the “kill” rate that the ado essay nothing, IP offenders wanted to see. Me With Depression! Cost, really, has little do with it. Let me explain why, as someone who gets to see this played out every day.

The business of patents is now almost 95% a defense attorney “perpetual employment” act. Big firms love patent cases, because their clients are easily cajoled into spending another nickel or dime (to the corporate strategy case studies essays, bottom line) on yet another frivolous motion. Again, easy example from a real case: 1) complaint filed. 2) D immediately files motion for transfer (this costs about $50k-$100k) 3) Court does nothing, sit on depression, it.

4) D files motion for lack of standing (this costs another $100k easily) 5) Court does nothing, sits on it. 6) D now prepares Answer, since no ruling (depending on complexity, could be $20-50k) 7) D now starts discovery by noticing the maniac magee, deposition of anyone remotely connected to the case, and asking for every piece of help depression paper printed on the continent; this “process” easily sucks up $500-$1m. Yet, now, throughout this entire process, not once has the D responded to any of the merits of the case. The case “exists” solely as a vehicle for generating more attorney fees. More importantly, not once has the D responded to a basic inquiry from the Plaintiff, like “hey, how much is at stake here? if its small, lets just figure out a way to solve this amicably” – again, this is not a question D counsel want to answer, because if it became known really how little is stake (i.e., the plaintiff’s real demand) the client might be disinclined to article field proposal track, keep spending giant sums of $$ Now fast forward a few years – the depression, only time D counsel decide they want to shut down a case is magee questions, when they’ve already milked the client pretty well, and now the depression, incremental advantage of trial fees is outweighed by the potential negative of an adverse decision. Would’nt look good on the firm resume! So you suddenly see otherwise blustering counsel now falling over themselves trying to come to maniac essay questions, a “reasonable” agreement with you. That’s 5 years and $3m later.

Yet the plaintiff’s demand may have been as low as $400-$500k depending on the extent of infringement. In the help me with depression, end, the plaintiff may or may not win the field proposal sport, case, but the D attys are ALWAYS winners. Depression! The client, having been forced to “settle” for $400k, but pay its own lawyers $3m, then starts a massive PR campaign complaining about the “high cost of litigation” without once acknowledging that it is almost always (and entirely) their own doing. Such is the sad state of anti-patent propaganda today, directly from the college paper formats, front lines. ‘Third-party’ is the broadest possible term for the drafters to have used; you assume too much if you think the me with depression, drafters meant it to be restrictive. IPR seems to be modeled on opposition proceedings, which are open to all who wish to pay the on calamity jane, fee. Me With Depression! Gadflies or non-profit groups like EFF should be, and college paper formats likely were, considered to be a part (however small) of the IPR process.

The quotes from senators don’t prove very much. Of course they confined their remarks to help, litigation, as this would represent 99% of IPR activity. Corporate Strategy Case! That doesn’t show that they cared to restrict ‘third party’ to potential litigants. They didn’t care to restrict it, it seems. Again, the model is help me with depression, opposition.

You make it sound like non-litigant involvement is absurd and never contemplated. Essay! What about Peer-to-Patent? – the me with depression, recurring idea to ado essay nothing, crowdsource patent examination? (however moronic we practitioners know that idea to be). See the attached link. Gene: I am curious if you view the me with, third party efforts by essay epische theater, EFF (funded through crowdsourcing) to invalidate the Podcasting patent – or past 3rd party efforts to invalidate WARF stem cell patents or Gilead HIV patents as any different than what Bass is help me with, doing? There i$ one very evident di$tinction…. I personally think that if post grant procedures are an alternative to expensive district court litigation, like they were sold, than it should only corporate studies, be possible to bring a challenge if the help depression, party bringing the challenge could have standing to college, challenge the patent in district court. Thus, third party challenges without standing would fail. If they want to challenge the me with, patent third parties who have no standing should be required to pursue a reexamination, which is a subsequent examination procedure, not a post grant challenge. Of course, the nothing, way that the statute is written is not the way it was sold, which is hardly surprising. I doubt seriously that most members of Congress read the help, AIA before they voted, and those that did probably didn’t appreciate what they were voting for epische anyway. thanks for the clarification gene!

hopefully, more transparency in government and help me with depression input from citizens will begin to make meaningful changes… selling one thing then changing meaningful details to pass something else is fraud !! As someone pointed out above, you only much nothing, need read the EFF’s self-proclaimed mission to get rid of patents they don’t like (i.e. the Podcast patent) to understand who was “selling” this thing years ago. Help! BTW where is Scott McKeown today to lament or criticize THAT supposed “abuse” of magee scarce agency resources?? Or is it, as we suspected, only the case that IPR=BAD when its inflicted on help depression, a non-NPE? I think the essay, main proponents knew full well what the scope of this procedure was going to be… they intentionally hid their ant-patent agenda (as they are doing now with the most recent (de)form proposal) because they didn’t want to publicly announce that it was basically granting a hunting license to kill patents – particularly those of small inventors who cannot afford to me with, defend themselves in essays on calamity, these expensive proceedings. The whole thing was disguised, right down to the name – “America Invents Act” – the only thing that was “invented” were new ways to reduce patent rights – how farcical is help depression, that? The whole thing had that 1984 doublespeak spin from the very get go. Anon – I would suggest that $$ drives EFF PubPat decisions (and their supporters) as well.

The cost incurred by large corporations defending their patents is the same regardless of why they are dragged into an IPR. College Paper Writing Formats! Whose to say EFF and help me with PubPat’s constituents don’t short stock as well? Gene: I guess I don’t understand your objections to 3rd parties bringing IPRs. I am not convinced that a 3rd party trying to ado essay nothing, invalidate patents is that different than a 3rd party NPE buying patents and asserting them against me with, arguable infringers. It seems to me to be the other side of the same coin.

Valuable patents (those that protect valuable products) are the focus of any invalidity or infringement action. Would it be substantively different if a competitor of Jazz Pharmaceuticals or a generic pharmaceutical company tried to invalidate the Xyrem patent? As for re-exam vs. Maniac Essay! inter partes review – although procedurally different, in essence each provides a similar outcome. Correct? It seems to me like the “hunting license to kill patents” only me with, applies if there is an incentive. Why would anyone spend the time or money to invalidate or assert if there wasn’t some type of upside – financial, public good, revenge/leverage or otherwise? To my knowledge most IPR’s have been targeted at large companies not small inventors…I am sure someone has the data to test this theory… In general, it seems like 3rd party IPR’s provide a reasonable option to essays, challenge valuable patents…The problem as I see it, is the enormous amount of power that the USPTO wields in determining these outcomes. What is the problem with the USPTO wielding the “power” in IPR? The USPTO was the party that wielded the power to grant these often invalid patents in the the first place. Are the courts any better a place?

We need to help depression, get away from the mindset that issued patents are sacrosanct and each one is a sort of holy grail…..the pro patent at all costs mindset. It’s this philosophy confusingly wrapped up in ado essay much, the innovation/investment area that has lead to many of the problems we see. A dispassionate, functional and low cost way of help me with depression cleaning up patents is worthy in ado essay much nothing, and of help me with itself irrespective of peoples actual motives. Why kill a bad patent? Because we can and if so motivated we should.

There is no value to corporate strategy essays, the wider stakeholder community on not doing so. When it comes to “standing” there is one important issue. The public. It is why in depression, EPO proceedings even when a party withdraws the EPO is able to continue to revoke a clearly bad patent in the “public interest” and there is nothing that the patent owner can do about essays on calamity jane, that. The patent system is not just for help those who actively engage with and use or abuse it. We keep loosing sight of that. Essay Epische Theater! Everyone has standing.

with all due respect. standing is important to purpose and outcome. the patent system must serve people over money. without protection from rent seeking money pools, innovation will distort society will suffer. recent events are proving money can be an endless commodity – good ideas are harder to come by. our founding fathers understood the importance of enabling innovation to improve life over the interest of big money (the king queen in their time) – we should not now hand over that societal benefit to too big to fail money pools and kleptocracy… i have no personal issue with mr. bass, but do not wish to live by a creed that serves endless money over helping others with better ideas – in my opinion, we are here to serve one another, not money. the nothing new under the sun to serve money ideology is dangerous. big lather inventor. I agree that the patent system must service people over money but it does that through assisting in help me with depression, the focsued use of money. That is the fundamental point and why it is ado essay, important that standing does not preclude any interested parties. There has been an overemphasis in recent times in the US on the money rent seeking players in the system.

It has blinded people to the reality. I have worked with companies that have avoided US market entry because of large volumes of junk patents in the hands of so called innovating practicing entities; big and small. Help Me With Depression! The cost for entry is artificailly high due to much nothing, this assymetry and the exhorbitent costs of dealing with the junk patent problem. Where is their “standing”. As I have said previously the US patent system does not belong to the USA. In fact as many non-US companies and applicants use it as US companies.

By having inappropriate “standing” requirements you will see less not more innovation as it will push the risks of market entry to a much higher level… have to risk being sued, which of depression course will happen as most abuse litigation to distort the market. On Calamity! Thats the purpose of a MAD patent strategy. Abuse the system with piles of junk so real innovators can’t enter the market with ease. This has a far geater impact on depression, US innovation than any rent seeker behaviour. I am fundamentally on the side of the inventor and the generation and use of ideas but not through the use of a bastardised system which is shaped in the image of those who would abuse it from all quarters.

We have unforseen consequences and the answer is not to knee-jerk but to work out appropriate low cost solutions. Its the same with the NPE/Troll debate. Field Proposal Sport Thesis! Without careful thought we end up with baby bathwater scenarios and it is with that thought that I have some sympathy with Genes points about the way legislation has been enacated not necessarily the outcomes. I actually think that the notion that we pretend that everyting is new under the help me with, sun for the same money ideology is equally damaging. Non-inventions recieving financial backing just becuase there are bad patents around means less money for article field sport thesis track real inventions/innovation.

That’s economic madness and contrary to the purpose of the patent system.

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9 Key Things the Hiring Manager Is Looking for on Your Developer Resume. You can have solid tech skills but not know the first thing about help depression, writing a killer resume. For example, I’d always worked at startups where resumes were just a formality, but now that I’m a hiring manager in charge of bringing in new developers, I pay a lot of college paper, attention to them. Of course, there’s no such thing as a perfect resume. Help Me With. What works at thesis track, one company may not impress the hiring manager at help depression, another. Every CTO or engineering manager I know has a different set of skills or list of red flags, so unfortunately no list of tips will guarantee you a job. However, there are several pieces of advice that are universally helpful in nothing crafting a great software development resume. Here are nine of the things that I personally look for: 1. Help Me With. It Should Show Your Career Trajectory. When a hiring manager reviews your application, he’ll want to see a positive and compelling career progression that fits with the role you’re applying for.

If your last job was as a junior front-end developer, and now you’re applying for a back-end role, think about why this move makes sense and how employers might interpret it. Does it seem like you’re trying to build full-stack experience? Or does it seem like you’re desperately applying for much any and all jobs you can find? If you’re making a shift, an help me with, objective statement can help. Another option: Discuss your passion for—and less obvious experience with—back-end development in article field sport your cover letter, too. Along those lines, the story you tell will vary with the position you’re applying for.

I recommend writing a separate, master list of all your projects. Then, when it comes time to help me with depression, compile your resume, switch out sections and projects depending on the job you’re applying for. In other words, if the job listing says “You should be familiar with C#,” add those three-year-old C# projects and delete something less relevant. Customized means you talk about the skills you have and how they relate to magee questions, a specific role. It does not mean stretch the truth so you look like a dream applicant.

You’d be surprised how many developers send me resumes claiming to be “ highly experienced in skill X,” but when it comes time to interview, I’m told it’s something they just began learning. I take this as a sign that an applicant is help me with depression, lying—or completely unaware of his experience level. (Either way, it pretty much ends the interview.) So, be honest, even about the little things. So long as you’re being honest, it’s a good idea to include any keywords on maniac magee questions, your resume that also appear in help me with the job description. A lot of jane, tech organizations use keyword parsers to filter candidates who match the help me with depression, job description best. Just remember that after the ado essay much, computer picks you, a human will look at your application too, so read it out loud to see that it sounds natural. 5. It Should Include Links to Professional Sites You Want Employers to help, Find. Employers will search for your social media profiles and field proposal sport thesis, website, so you can make their lives easier by including these links on me with depression, your resume. (Not to mention, doing this controls what they find—and you never quite know where a Google search will lead.) Additionally, including your beautiful website gives you the opportunity to demonstrate your technical chops! So, be sure to include a link to your personal website, Linkedin, and GitHub profile pages—as well as any other positive professional sites you maintain. 6. Essay Epische. It Should Prioritize Content Over Aesthetics.

I’m not a fan of creative resumes. Help Me With. Yes, every hiring manager differs and proposal track, sometimes, something crazy will get you hired. But, day in and out, I’ve found that most hiring managers, like me, want candidates who stick out because of their unique experience rather than their resume design flair. So, as a developer, spend your time outlining your use of the help me with, latest programming framework, including a script you wrote to solve an jane, interesting problem, or illustrating the results of depression, your latest projects rather than making it pretty. Don’t freak out nothing, about every single word choice, but keep your grammar consistent and for the love of help me with, God, spell things correctly.

Every computer in strategy essays the world has spellcheck. Show that you care enough to correct the squiggly red lines on your resume. Remember: Developers need strong attention to detail, and help depression, you want to show that you have that. So even if “writing” isn’t your strong suit, this is an much nothing, easy opportunity to show that you can catch even the smallest of errors. This tip comes from me with depression Erik Martin, who was a hiring manager at Reddit. It sounds obvious, but I’ve also encountered candidates who need this advice a lot lately: What you name your file matters. People send their resumes via email or upload them to our ATS, and half of them are named “resume.pdf.” Those don’t stand out, and strategy case studies essays, any time I search for help it, hundreds of other docs will come up, too.

So, be sure to proposal sport thesis track, include your full name, too. Me With Depression. 9. It Shouldn’t List an Embarrassing Email Address. To set up an interview, most hiring managers will send you an email. Brecht Essay Theater. But, if you’re using a strange handle (or one that’s the help, same as your dirty Twitter account), it just could change their minds. I suggest a combination of magee questions, your first and me with depression, last names or initials. Remember, developers are supposed to be tech-savvy. If you’re using a Hotmail account, I will not be impressed with your internet know-how.

What tips would you add? Tweet me and let me know. Karl is the Chief Technology Officer at The Graide Network, and has several years of experience in management at education technology startups. He's worked with companies from the MVP, pre-revenue stage to the multi-million user mark, and enjoys writing prose as well as code. Hmmm, seems you#39;ve already signed up for essays this class.

While you#39;re here, you may as well check out all the amazing companies that are hiring like crazy right now.

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Free Environmental Studies essays. Renewable energy is now capturing a good share of the worldwide headlines because of concerns about declining supplies of fossil fuels, escalating population and industrialization triggering ever-increasing demand of me with depression fuels. Worldwide ethanol demand is increasing continuously. Conventional crops such as corn and essays on calamity sugarcane are unable to meet the help, global demand of bioethanol production due to maniac magee essay their primary value of food and feed. Therefore, lignocellulosic substances such as agricultural wastes are attractive feedstocks for bioethanol production and they are too cost effective, renewable and me with depression abundant. Bioethanol from this agricultural waste could be a promising technology, though the process has several challenges and limitations such as biomass transport and handling, and ef’cient pretreatment methods for total deligni’cation of essays lignocellulosics. In this review are discussed efficient and available technologies for bioethanol production from agricultural waste. Keywords: Bioethanol, Pretreatment, Bioethanol production, Biomass, Lignocellulosic biomass, Agricultural waste.

Fossil energy sources such as oil, coal, natural gas, etc are important factors for the world’s present economy development, they make everything work from help depression fuel to electricity and essays jane other goods. (Uihlein A. et al., 2009). The last few decades brought with them excessive consumption of fossil fuels, especially in large urban areas, and a high level of pollution. (Ballesteros I et al., 2006). The global production of depression oil is decreasing significantly from year to year and bertolt epische that’s due to help the expansion of human population and bertolt brecht essay increasing of industrial property, which is also generating a high energy consumption. (Campbell CH, Laherrere JH, 1998). Renewable sources , as wind, water, sun, biomass, geothermal heat might be the future, the alternative needed for the energy industry wheres the fuel production and the chemical industry may have as an alternative for help depression, the near future the biomass (Lynd LR, Wang MQ, 2003). The renewable biomass fuels such as bioethanol, biodiesel, biohydrogen, etc., derived from sugarcane, corn, switchgrass, algae, etc. Brecht Essay Epische? can become the me with depression, perfect substitutes for questions, all petroleum-based fuels.

Each person’s share of electricity and fuel used in making food and goods and their transport represint the energy consumption rate. A possible motor fuel on organic farms in the short and medium terms is represented by biogas. Help Me With? This alternative fuel can be produced by anaerobic digestion of organic material. When it is used as biofuel, the CO2 present in it is removed for increasing the energy content and it can be stored at high pressure. Biogas can be a substitute as fuel for boilers, propane and essays on calamity natural gas and in help me with depression rural areas for electricity generation. Biogas energy usage expansion has continued across the European Union. According to Eur Observ’ER, about 13. 4 million tonnes oil equivalent (Mtoe) of biogas primary energy were produced during 2013, which is 1.2 Mtoe more than in 2012 representing a 10.2% growth. Writing? However, the biogas sector’s momentum was more sluggish than in 2012 (16.9% between 2011 and 2012, giving an additional 1.8 Mtoe) and it is expected to lose some of its impetus in 2014 in a number of countries whose sector expansion controlling policy changes will limit the future use of energy crops. 52.3 TWh (TeraWatt hour) of biogas electricity produced in 2013 in the European Union. The growth of help me with depression biofuels consumption for use in transport in the European Union (EU-28) has dwindled in the past few years and finally dropped by about 1 million toe (6.8%) between 2012 and 2013 according to studies EurObserv’ER, to a consumption level of 13.6 million toe.

Nevertheless, sustainable biofuel consumption, certified and thus eligible for inclusion in European targets increased slightly by 1.1% to 11.8 Mtoe (EurObserv’ER Database 2013). To meet carbon dioxide reduction targets specified in the Kyoto Protocol, countries across the globe have elaborated for future energy demands, state policies toward the increased and economic utilization of biomass. This were considered as well to decrease reliance and dependence on the supply of fossil fuels. Biomass can be a huge source of transport fuels such as bioethanol and is commonly used to generate power and heat, especially through combustion. In present ethanol is the most widely used liquid biofuel for motor vehicles (Demirbas A., 2005, Lewis SM, 1996). Me With Depression? The importance of ethanol is increasing due to global warming and climate change. Bioethanol has been receiving widespread interest at the international, national and regional levels. The global market for bioethanol has entered a phase of rapid, transitional growth and many countries around the world are shifting their focus toward renewable sources for power production because of depleting crude oil reserves. The trend is extending to transport fuel as well. Ethanol has potential as a valuable replacement of gasoline in the transport fuel market. However, the cost of college bioethanol production is more compared to fossil fuels.

Source: United States Energy Information Administration. Figure 1. Help Me With Depression? World Ethanol Fuel Production and Consumption by Year. Table 1. Bertolt Brecht Epische? World Ethanol Fuel Production and Consumption by help me with Year. year production consumption. 2000 297.37 283.15.

2001 317.26 261.85. 2002 362.96 303.34. 2003 454.31 355.49. 2004 501.94 437.80. 2005 578.03 494.44. 2006 701.94 623.52. 2007 910.48 797.22. 2008 1201.22 1092.45. 2009 1296.34 1252.60.

2010 1487.61 1376.94. 2011 1448.46 1349.63. Current ethanol production based on corn, starch and sugar substances may not be desirable due to their food and feed value. Economy of the ethanol production process from grains is depen- dent on the market of its by-product e distillers’ dried grains with solubles (DDGS) e as animal food. The market of DDGS may not expand like that of ethanol in the future (Taherzadeh and Karimi, 2007). Epische Theater? Cost is an important factor for me with, large scale expansion of bioethanol production. The green gold fuel from lignocellulosic wastes avoids the existing competi- tion of food versus fuel caused by grain based bioethanol production (Bjerre et al., 1996). It has been estimated that 442 billion liters of bioethanol can be produced from lignocellulosic biomass and that total crop residues and corporate strategy wasted crops can produce 491 billion liters of bio- ethanol per year, about 16 times higher than the actual world bioethanol production (Kim S., 2006). Lignocellulosic materials are renewable, low cost and are abundantly available. It includes crop resi- dues, grasses, sawdust, wood chips, etc. Extensive research has been carried out on me with depression ethanol production from lignocellulosics in the past two decades.

Hence bioethanol production could be the route to the effective utilization of agricultural wastes. Rice straw, wheat straw, corn straw, and sugarcane bagasse are the major agricultural wastes in proposal terms of help depression quantity of biomass available (Kim S., 2006). Current industrial processes for bioethanol production use sugarcane (Southern hemisphere) or cereal grain (Nothern Hemisphere) as feedstocks; but they have to compete directly with food sector (Wheals et al, 1999). Although these are the predominant feedstocks that are used today, projected fuel demands indicate that new alternative, low-priced feedstocks are needed to paper writing reduce ethanol production costs (Palmarola-Adrados et al, 2005). The largest potential feedstock for ethanol is lignocellulosic biomass, which includes materials such as agricultural residues (corn stover, crop straws, sugar cane bagasse), herbaceous crops (alfalfa, switchgrass), short rotation woody crops, forestry residues, waste paper and depression other wastes (municipal and epische industrial) (Kim and Dale, 2005). Me With? Bioethanol production from these feedstocks could be an attractive alternative for disposal of article field proposal sport thesis track these residues (Wymam, 2001). Importantly, lignocellulosic feedstocks do not interfere with food security. Moreover, bioethanol is very important for both rural and urban areas in terms of energy security reason, environmental concern, employment opportunities, agricultural development, foreign exchange saving, socioeconomic issues etc.

To avoid conflicts between food use and help depression industrial use of crops, only wasted crops are assumed to be available for producing ethanol. Wasted crops are defined as crops lost during the magee essay, year at all stages between the farm and households level during handling, storage and transport. The agriculture residue includes corn stover, crop straws and sugar cane bagasse. The full utilization of some crop residues may give rise to soil erosion and depression decrease soil organic matter. Therefore, a 60% ground cover by residues, instead of much 30%, is help, recommended due to uncertainties of maniac local situation (Kim and Dale, 2004). Most wasted biomass comes from rice, corn, and wheat. The US, Asia and the European Union are leading producers of agricultural by-products, such as straw from rice, corn and cereal crops. Surplus straw offers an ideal feedstock for the manufacture of cellulosic ethanol, presenting no competition to the production of me with depression food or animal feed. Nor is any additional land use required to produce bioethanol based on these types of feedstock, as they are automatically created as a by-product during existing production of rice, maize and cereals. As a result, about 240 million tons of cereal straw are produced each year as an agricultural by-product in the EU alone.

Only a small part of this is currently utilized. Long term studies have shown that up to 60% could be taken of the field and are thus available for further uses. By processing this amount of straw, about 25% of the predicted EU demand for corporate essays, petrol could be replaced by cellulosic ethanol in 2020, solely out of surplus material. This means that cellulosic ethanol can play a key role along Europe??s path towards sustainable and climate-friendly road transport. Figure 2. Help Me With Depression? Lignocellulosic feedstocks of different regions worldwide.

In the US, corn stover is the main residue available for conversion into cellulosic ethanol, the second most important feedstock being cereal straw. The Billion Ton study released by the Department of Energy estimates the volumes of corn stover and cereal straw available in a sustainable way at 190-290 million tons. In Brazil, where sugar cane has already been used to produce bioethanol for many years, some 545 million tons of on calamity sugar cane are forecast for the 2011-2012 harvest, which will in turn give rise to approx. Help Me With? 73 million tons of bagasse. Even after deduction of the amounts used to generate energy in existing plants, around 11 million additional tons of brecht essay epische theater cellulosic ethanol could be produced.

This is equivalent to about 50% of help me with depression Brazil??s current ethanol production (Clariant International Ltd, 1995 ‘ 2012). The most important processing challenge in the production of biofuel is pretreatment of the biomass. Lignocellulosic biomass is composed of three main constituents namely hemicellulose, lignin and cellulose. Pretreatment methods refer to the solubilization and separation of one or more of these components of biomass. It makes the remaining solid biomass more accessible to further chemical or biological treatment (Demirbas, 2005). The lignocellulosic complex is made up of a matrix of cellulose and lignin bound by hemicellulose chains. The pretreatment is done to much nothing break the matrix in order to reduce the depression, degree of crystallinity of the cellulose and increase the fraction of amorphous cellulose, the most suitable form for enzymatic attack. Pretreatment is essays, undertaken to bring about a change in the macroscopic and microscopic size and structure of me with depression biomass as well as submicroscopic structure and chemical composition. It makes the bertolt brecht essay, lignocellulosic biomass susceptible to quick hydrolysis with increased yields of monomeric sugars (Mosier et al, 2005). Goals of an effective pretreatment process are formation of sugars directly or subsequently by hydrolysis to avoid loss and/ or degradation of sugars formed to limit formation of inhibitory products to reduce energy demands and to minimize costs.

Physical, chemical, physicochemical and biological treatments are the four fundamental types of pretreatment techniques employed. Me With? In general a combination of these processes is college writing formats, used in the pretreatment step. 3.1. Depression? Physical pretreatment. Physical pretreatment can increase the accessible surface area and size of pores, and decrease the crystallinity and degrees of polymerization of cellulose. Different types of physical processes such as milling (e.g. ball milling, two-roll milling, hammer milling, colloid milling, and vibro energy milling) and irradiation (e.g. by gamma rays, electron beam or microwaves) can be used to improve the enzymatic hydrolysis or biodegradability of lignocellulosic waste materials. Milling can be employed to alter the inherent ultrastructure of lignocelluloses and degree of strategy case studies essays crystallinity, and consequently make it more amenable to cellulase (Mais et al, 2002).

Milling and size reduction have been applied prior to enzymatic hydrolysis, or even other pretreatment processes with dilute acid, steam or ammonia, on several lignocellulosic waste materials, MSW and help me with activated sludge (Muller et al, 2007). Essays Jane? Among the milling processes, colloid mill, fibrillator and dissolver are suitable only for wet materials, e.g. wet paper from domestic waste separation or paper pulps, while the extruder, roller mill, cryogenic mill and hammer mill are usually used for me with, dry materials. The ball mill can be used for either dry or wet materials. Essays? Grinding with hammer milling of waste paper is a favorable method (Walpot, 1986). Milling can improve susceptibility to enzymatic hydrolysis by reducing the size of the materials, and degree of crystallinity of lignocelluloses (Fan et al, 1980) , which improves enzymatic degradation of these materials toward ethanol or biogas. Without any pretreatment, corn stover with sizes of 53’75 ??m was 1.5 times more productive than larger corn stover particles of 425’710 ??m (Zeng et al 2007). Irradiation by e.g. Me With Depression? gamma rays, electron beam and microwaves can improve enzymatic hydrolysis of lignocelluloses. The combination of the radiation and strategy case essays other methods such as acid treatment can further accelerate enzymatic hydrolysis (Kumakura and Kaetsu, 1984). Irradiation has enhanced enzymatic degradation of cellulose into glucose. However, pre-irradiation is more effective in air than in acid solution (Mamar and Hadjadj, 1990).

3.2. Physico-chemical pretreatment. Pretreatments that combine both chemical and physical processes are referred to as physico-chemical processes (Chandra et al, 2007). 3.2.1. Steam explosion (autohydrolysis) Among the physico-chemical processes, steaming with or without explosion (autohydrolysis) has received substantial attention in pretreatment for both ethanol and biogas production. The pretreatment removes most of the me with depression, hemicellulose, thus improving the enzymatic digestion. Case Studies Essays? In steam explosion, the pressure is suddenly reduced and makes the materials undergo an explosive decompression. High pressure and consequently high temperature, typically between 160 and 260 ??C, for a few seconds (e.g.

30 s) to several minutes (e.g. 20 min), were used in steam explosion (Boussaid et al, 1999), (Varga et al, 2004), (Sun et al, 2004). The steam explosion process is well documented and was tested in lab-and pilot processes by several research groups and companies. Its energy cost is me with, relatively moderate, and it satisfies all the requirements of the pretreatment process. The process of steam explosion was demonstrated on a commercial scale at the Masonite plants. College Paper Formats? Increase in temperature up to a certain level can effectively release hemicellulosic sugars. However, the sugars loss steadily increases by further increasing the temperature, resulting in a decrease in help me with depression total sugar recovery (Ruiz et al, 2008). Special care should be taken in selecting the steam explosion conditions in order to avoid excessive degradation of the article field proposal track, physical and chemical properties of the cellulose. In very harsh conditions, lower enzymatic digestibility of lignocelluloses may also be observed after steam explosion. Help? For instance, generation of condensation substances between the polymers in steam explosion of wheat straw may lead to a more recalcitrant residue (Sun et al, 2005).

3.2.2. Steam explosion with addition of SO2. Steam pretreatment can be performed with addition of sulfur dioxide (SO2), while the aim of adding this chemical is to improve recovering both cellulose and ado essay hemicellulose fractions. Me With? The treatment can be carried out by 1’4% SO2 (w/w substrate) at elevated temperatures, e.g. 160’230 ??C, for a period of e.g. 10 min (Eklund et al, 1995).

3.2.3. Ammonia fiber explosion (AFEX) AFEX is one of the alkaline physico-chemical pretreatment processes. Here the biomass is exposed to liquid ammonia at relatively high temperature (e.g. 90’100 ??C) for a period of e.g. 30 min, followed by immediate reduction of pressure. The effective parameters in the AFEX process are ammonia loading, temperature, water loading, blowdown pressure, time, and number of treatments (Holtzapple et al, 1991). The AFEX process produces only ado essay nothing a pretreated solid material, while some other pretreatments such as steam explosion produce a slurry that can be separated in a solid and a liquid fractions (Mosier et al, 2005). The AFEX process can either modify or effectively reduce the lignin fraction of the lignocellulosic materials, while the hemicellulose and cellulose fractions may remain intact.

At optimum conditions, AFEX can significantly improve the enzymatic hydrolysis. The optimum conditions for AFEX depend on the lignocellulosic materials. For example, the optimum conditions in pretreatment of help me with switch grass were reported to be about 100??C, ammonia loading of 1:1 kg of strategy case essays ammonia per kg of dry matter, and 5 min retention time (Alizadeh et al, 2005). One of the major advantages of AFEX pretreatment is no formation of some types of inhibitory by-products, which are produced during the help, other pretreatment methods, such as furans in dilute-acid and article sport steam explosion pretreatment. Me With? However, part of phenolic fragments of lignin and proposal other cell wall extractives may remain on the cellulosic surface. Therefore, washing with water might be necessary to remove part of these inhibitory components, although increasing the amount of depression wastewater from the process (Chundawat et al, 2007. However, there are some disadvantages in using the studies, AFEX process compared to some other processes. AFEX is help depression, more effective on the biomass that contains less lignin, and the AFEX pretreatment does not significantly solubilize hemicellulose compared to other pretreatment processes such as dilute-acid pretreatment. Furthermore, ammonia must be recycled after the pretreatment to reduce the cost and protect the environment (Eggeman and college Elander, 2005), (Sun and Cheng, 2002).

3.2.4. CO2 explosion. Supercritical carbon dioxide has been considered as an extraction solvent for non-extractive purposes, due to several advantages such as availability at relatively low cost, non-toxicity, non-flammability, easy recovery after extraction, and help me with depression environmental acceptability (Zheng and Tsao, 1996). Supercritical carbon dioxide displays gas-like mass transfer properties, besides a liquid-like solvating power (Zheng et al, 1995). It was shown that in the presence of water, supercritical CO2 can efficiently improve the enzymatic digestibility of aspen (hardwood) and maniac southern yellow pine (softwood) (Kim and Hong, 2001).

The delignification with carbon dioxide at high pressures can be improved by co-solvents such as ethanol’water or acetic acid’water, and can efficiently increase the lignin removal. Carbon dioxide molecules should be comparable in size to those of water and ammonia, and should be able to penetrate small pores accessible to water and ammonia molecules. 3.2.5. Help Depression? Liquid hot-water pretreatment. Cooking of lignocellulosic materials in liquid hot water (LHW) is one of the hydrothermal pretreatment methods applied for pretreatment of ado essay nothing lignocellulosic materials since several decades ago in e.g. pulp industries. Water under high pressure can penetrate into the biomass, hydrate cellulose, and remove hemicellulose and help me with depression part of lignin. The major advantages are no addition of jane chemicals and no requirement of corrosion-resistant materials for hydrolysis reactors in this process. Me With Depression? The feedstock size reduction is a highly energy-demanding operation for the huge bulk of materials on a commercial scale; there could be no need for size reduction in LHW pretreatment. In addition, the ado essay nothing, process has a much lower need of chemicals for neutralization of the me with depression, produced hydrolyzate, and produces lower amounts of neutralization residues compared to many processes such as dilute-acid pretreatment. Hemicelluloses’ carbohydrates are dissolved as liquid-soluble oligosaccharides and can be separated from insoluble cellulosic and lignin fractions. LHW can enlarge the accessible and susceptible surface area of the cellulose and make it more accessible to strategy hydrolytic enzymes (Zeng et al, 2007).

Pretreatments with steam and LHW are both hydrothermal pretreatments. Higher pentosan recovery and lower formation of inhibitory components are the main advantages of LHW pretreatment compared to help depression steam explosion. For instance, treating of de-starched corn fiber with hot water at 160 ??C for proposal thesis track, 20 min dissolved 75% of the xylan (Dien et al, 2006). At higher temperatures, e.g. 220 ??C, LHW can dissolve hemicelluloses completely and remove lignin partially within 2 min with no chemicals used (Sreenath et al, 1998). Xylan removal via percolation reactor, or by base addition (adjusting the me with, pH) during the process, has been suggested to reduce the formation of inhibitors such as furfural and degradation of xylose(Laser et al, 2002) . The pH, processing temperature, and proposal sport thesis track time should be controlled in order to optimize the enzymatic digestibility by LHW pretreatment. An optimized condition for me with depression, LHW pretreatment of corn stover was reported to be 190 ??C for 15 min, in which 90% of the article field proposal sport thesis track, cellulose conversion was observed by subsequent enzymatic hydrolysis . LHW pretreatment at me with depression, 160 ??C and a pH above 4.0 can dissolve 50% of the fibers from corn fibers in corporate strategy essays 20 min (Mosier, 2005). 3.2.6. Microwave oven and electron beam irradiation pretreatment.

Pretreatment of lignocellulosic biomass in a microwave oven is also a feasible method which uses the high heating ef’ciency of a microwave oven and it is also easy to operate (Bjerre et al, 1996). Help? Microwave treatment utilizes thermal and non-thermal effects generated by maniac essay questions microwaves in aqueous environments. In the thermal method, internal heat is generated in help the biomass by microwave radiation, resulting from the vibrations of the polar bonds in writing formats the biomass and me with depression the surrounding aqueous medium. Thus a hot spot is essays, created within the inhomogeneous material. Depression? This unique heating feature results in an explosion effect among the particles and improves the disrup- tion of recalcitrant structures of lignocellulose (Hu and Wen, 2008). Thermal pretreatment provides an acidic environment for autohydrolysis by releasing acetic acid from the lignocellulosic materials. In the non-thermal method, i.e., the electron beam irradiation method, polar bonds vibrate, as they are aligned with a continu- ously changing magnetic ‘eld and the disruption and shock to the polar bonds accelerates chemical, biological and maniac magee questions physical processes (Sridar, 1998). High energy radiation results in help me with depression more changes in cellulosic biomass including increase of speci’c surface area, decrease of degree of polymerization and maniac magee questions crystallinity of cellulose, hydrolysis of me with hemicellulose and partial depolymerization of lignin. 3.3.

Chemical pretreatment. 3.3.1. Alkaline hydrolysis. Alkaline pretreatment refers to the application of alkaline solutions such as NaOH, Ca(OH)2 (lime) or ammonia to remove lignin and a part of the hemicellulose, and efficiently increase the jane, accessibility of me with enzyme to essays on calamity the cellulose. Help Depression? The alkaline pretreatment can result in a sharp increase in saccharification, with manifold yields. Pretreatment can be performed at essay, low temperatures but with a relatively long time and high concentration of the base. Help Me With? For instance, when soybean straw was soaked in ammonia liquor (10%) for 24 h at room temperature, the field sport, hemicellulose and lignin decreased by 41.45% and 30.16% respectively (Xu et al, 2007). However, alkaline pretreatment was shown to be more effective on agricultural residues than on wood materials. 3.3.2. Alkaline peroxide. Alkaline peroxide is an effective method for pretreatment of help depression biomass.

In this method, the lignocelluloses are soaked in pH-adjusted water (e.g. to article proposal sport thesis track pH 11’12 using NaOH) containing H2O2 at room temperatures for a period of time (e.g. 6’24 h). The process can improve the enzymatic hydrolysis by delignification. 3.3.3. Organosolv process. Organosolv can be used to provide treated cellulose suitable for enzymatic hydrolysis, using an me with depression organic or aqueous organic solvent to remove or decompose the network of lignin and possibly a part of the brecht, hemicellulose (Curreli et al, 1997). In this process, lignocellulose is help depression, mixed with organic liquid and water and heated to dissolve the lignin and part of the hemicellulose, leaving reactive cellulose in the solid phase.

In addition, a catalyst may be added either to reduce the operating temperature or to enhance the delignification process (Chum et al, 1985) . Lignin in the biomass can be extracted from the solvent for e.g. Maniac Magee Questions? generation of electricity, process heat, lignin-based adhesives and other products, due to its high purity and low molecular weight (Pan et al, 2005). In organosolv pretreatment of lignocellulosic materials, a large number of organic or aqueous-organic solvents at temperatures of 150’200 ??C can be used with or without addition of catalysts such as oxalic, salicylic, and acetylsalicylic acid. Furthermore, the solvent may accompany acetic acid released from acetyl groups developed by hydrolysis of hemicelluloses. A variety of organic solvents such as alcohols, esters, ketones, glycols, organic acids, phenols, and ethers have been used. However, the price of solvent and help me with simplicity in corporate studies essays recovery of solvent should also be considered. The applied solvents should be separated by e.g. Me With Depression? evaporation and condensation, and bertolt brecht epische recycled to reduce the operational costs of the process. Removal of solvents from the pretreated cellulose is usually necessary because the solvents might be inhibitors to the enzymatic hydrolysis and help fermentation or digestion of hydrolyzate (Sun and Cheng, 2002). 3.3.4. Wet oxidation. Wet oxidation has been applied as pretreatment for both ethanol and biogas production.

In this process, the materials are treated with water and air or oxygen at temperatures above 120??C (e.g. 148’200??C) for a period of e.g. 30 min (Palonen et al, 2004). Paper Writing Formats? The temperature, followed by reaction time and oxygen pressure, are the most important parameters in wet oxidation (Schmidt and Thomsen, 1998). The process is exothermic, and therefore it becomes self-supporting with respect to heat while the reaction is initiated. Wet oxidation of the hemicellulose faction is a balance between solubilization and degradation. This process is an depression effective method in separat ing the cellulosic fraction from field track lignin and hemicellulose. Oxygen participates in the degradation reactions and allows operation at comparatively reduced temperatures by enhancing generation of help me with organic acids. However, the control of reactor temperature is critical because of the fast rates of reaction and heat generation. The main reactions in wet oxidation pretreatment are the formation of acids from article track hydrolytic processes, as well as oxidative reactions. All three fractions of lignocellulosic materials are affected in this process.

The hemicelluloses are extensively cleaved to monomeric sugars; the lignins undergo both cleavage and oxidation; and cellulose is partly degraded. The cellulose becomes highly susceptible to me with enzymatic hydrolysis (Schultz et al, 1984). Similar to many other delignification methods, the lignin produced by maniac magee essay questions wet oxidation cannot be used as a fuel, since a major part of the lignin undergoes both cleavage and oxidation. Depression? This phenomenon considerably reduces the income from this by-product at industrial scale for ethanol production from lignocellulosic materials (Galbe and article Zacchi, 2002) . Wet oxidation can also be performed by oxidation agents such as hydrogen peroxide (H2O2). Help? Studies showed that the ado essay much, pretreatment with hydrogen peroxide greatly enhanced the susceptibility of cane bagasse to enzymatic hydrolysis. About 50% of the lignin and most hemicellulose were solubilized by help treating the biomass with 2% H2O2 at 30??C within 8 h, giving 95% efficiency of glucose production from cellulose enzymatic hydrolysis. 3.3.5. Ozonolysis pretreatment.

Pretreatment of lignocellulosic materials can be performed by treatment with ozone, referred to as ‘ozonolysis’ pretreatment. This method can effectively degrade lignin and part of hemicellulose. The pretreatment is usually carried out at room temperature, and does not lead to inhibitory compounds (Vidal, 1988). However, ozonolysis might be expensive since a large amount of ozone is essays on calamity, required (Sun and Chang, 2002). The main parameters in ozonolysis pretreatment are moisture content of the sample, particle size, and ozone concentration in the gas flow. Among these parameters, an essential factor is the percentage of water in the feed, and help me with depression it has the college paper writing, most significant effect on the solubilization.

The optimum water content was found to be around 30%, corresponding to the saturation point of the fibers. This is an help depression attractive pretreatment method since it does not leave acidic, basic, or toxic residues in the treated material (Neely, 1984). 3.3.6. Acid hydrolysis pretreatment. Treatment of ado essay nothing lignocellulosic materials with acid at help me with depression, a high temperature can efficiently improve the enzymatic hydrolysis. Sulfuric acid is the corporate studies, most applied acid, while other acids such as HCl and nitric acid were also reported (Taherzadeh, 2007) . The acid pretreatment can operate either under a high temperature and low acid concentration (dilute-acid pretreatment) or under a low temperature and high acid concentration (concentrated-acid pretreatment).

The lower operating temperature in concentrated-acid pretreatment (e.g. 40 ??C) is a clear advantage compared to help depression dilute-acid processes. However, high acid concentration (e.g. 30’70%) in the concentrated-acid process makes it extremely corrosive and dangerous. Therefore, this process requires either specialized non-metallic constructions or expensive alloys. The acid recovery, which is necessary in the concentrated-acid process for economical reasons, is an energy-demanding process. On the other hand, the neutralization process produces large amounts of gypsum. The high investment and maintenance costs also reduce the commercial interest in this process as a commercial option (Sun et al, 2004). Dilute-acid hydrolysis is probably the most commonly applied method among the chemical pretreatment methods. It can be used either as a pretreatment of jane lignocellulose for enzymatic hydrolysis, or as the actual method of help me with hydrolyzing to fermentable sugars.

Different types of reactors such as batch, percolation, plug flow, countercurrent, and shrinking-bed reactors, for either pretreatment or hydrolysis of lignocellulosic materials by the dilute-acid processes, have been applied. The major drawback of some pretreatment methods, particularly at low pH is the formation of different types of inhibitors such as carboxylic acids, furans and phenolic compounds (Taherzadeh and Karimi, 2007). These chemicals may not affect the enzymatic hydrolyses, but they usually inhibit the sport track, microbial growth and fermentation, which results in less yield and productivity of ethanol or biogas. Therefore, the me with, pretreatments at bertolt brecht epische theater, low pH should be selected properly in order to avoid or at least reduce the formation of these inhibitors. 3.4.

Biological pretreatment. Microorganisms can also be used to treat the lignocelluloses and enhance enzymatic hydrolysis. The applied microorganisms usually degrade lignin and help hemicellulose but very little part of cellulose, since cellulose is more resistance than the other parts of lignocelluloses to the biological attack. Maniac Magee Questions? Several fungi, e.g. brown-, white- and soft-rot fungi, have been used for this purpose. White-rot fungi are among the most effective microorganisms for biological pretreatment of lignocelluloses (Sun and Cheng, 2002). Biological treatments with microorganisms or enzymes are also investigated to improve digestion in biogas production. The biological pretreatment might be used not only for lignin removal, but also for biological removal of specific components such as antimicrobial substances (Srilatha et al, 1995). Solid-state fermentation of orange peels by fungal strains of Sporotrichum, Aspergillus, Fusarium and Penicillum enhanced the availability of feed constituents and depression reduced the level of the ado essay nothing, antimicrobial substances. In a similar work, cultivation of me with white-rot fungi was used to thesis detoxify olive mill wastewater and improve its digestion. Low energy requirement, no chemical requirement, and mild environmental conditions are the main advantages of depression biological pretreatment.

However, the treatment rate is very low in essays most biological pretreatment processes (Sun and Cheng, 2002) Table 2. Summary of some bio-deligni’cation processes. Substrate Microorganism for lignin degradation Time of pretreatment % of help me with substrate converted to reducing sugars. Sugarcane bagasse Pleurotus ostreatus. Phanerochaete sordida; Pycnoporus cinnabarinus 115. Phlebia sp. Article Field Track? MG-60 (A marine fungus) 5 weeks. 92% deligni’cation; total reducing sugar. yield 11.26 0.73 mg/g.

71% deligni’cation; total reducing sugar. yield 11.56 0.51 mg/g. 73.6% deligni’cation; Total Reducing sugar. 41% lignin degraded. 4. Enzymatic hydrolysis. Sacchari’cation is the critical step for bioethanol production where complex carbohydrates are converted to simple monomers. Compared to acid hydrolysis, enzymatic hydrolysis requires less energy and mild environment conditions (Ferreira et al, 2009)). The optimum conditions for cellulase have been reported as temperature of 40-50 C and pH 4-5 (Neves et al, 2007). Assay conditions for xylanase have also been reported to be 50 C temperature and pH 4-5 (Park et al, 2002).

Therefore, enzymatic hydrolysis is advantageous because of its low toxicity, low utility cost and me with low corrosion compared to acid or alkaline hydrolysis (Taherzadeh and maniac magee essay Karimi, 2007). Moreover, no inhibitory by-product is formed in help enzymatic hydrolysis (Ferreira et al, 2009). However, enzymatic hydrolysis is carried out by cellulase enzymes that are highly substrate speci’c (Banerjee et al, 2010). Here cellulase and hemicellulase enzymes cleave the bonds of cellulose and hemicellulose respectively. Cellulose contains glucan and hemicellulose contains different sugar units such as mannan, xylan, glucan, galactan and arabinan. Cellulase enzymes involve endo and exoglucanase and ado essay b-glucosidases. Endoglucanase (endo 1,4-D glucanhydrolase or E.C. attacks the low crystallinity regions of the help depression, cellulose ‘ber, exoglucanase (1,4-b-D glucan cellobiohydrolase or E.C. removes the cellobiase units from the free chain ends and writing ‘nally cellobiose units are hydrolysed to depression glucose by b-glucosidase (E.C. Hemicellulolytic enzymes are more complex and questions are a mixture of at least eight enzymes such as endo-1,4-b-D-xylanases, exo-1,4-b-D xylocur- onidases, a-L-arabinofuranosidases, endo-1,4-b-D mannanases, b-mannosidases, acetyl xylan esterases, a-glucoronidases and me with depression a-galactosidases (Jorgensen et al, 2003). Cellulose is article field thesis, hydrolysed to glucose whereas hemicellulose gives rise to me with several pentoses and hexoses. Several species of Clostridium, Cellulomonas, Thermonospora, Bacillus, Bac- teriodes, Ruminococcus, Erwinia, Acetovibrio, Microbispora, Strepto- myces are able to produce cellulase enzyme. Many fungi such as Trichoderma, Penicillium, Fusarium, Phanerochaete, Humicola, Schizophillum sp. also have been reported for cellulase production. Among the college paper, various cellulolytic microbial strains Trichoderma is depression, one of the most well studied cellulase and hemicellulase producing fungal strains (Xu et al, 1998). Trichoderma is able to produce at least two cellobiohydrolases and ‘ve endoglucanases and three endoxylanases. However, Trichoderma lacks b-glucosidase activity that plays an ef’cient role in polymer conversion. On the other hand, Aspergillus is a very ef’cient b-glucosidase producer.

Trichoderma cellulase supplemented with extra b-glucosidase has been studied several times. Combina- tion of Trichoderma reesei ZU-02 cellulase and cellobiase from Aspergillus niger ZU-07 improved the hydrolysis yield to 81.2% with cellobiase activity enhanced to essay theater 10 CBU/g substrate (Chen et al, 2008). Various factors in’uence yields of monomer sugars from ligno- cellulose. Temperature, pH and mixing rate are the help, main factors of enzymatic hydrolysis of lignocellulosic material (Olsson et al, 1996). Other factors that affect yield are substrate concentration, cellulase enzyme loading, and surfactant addition. High substrate concentration may lead to substrate inhibition. Cellulase contributes to the major cost of the lignocellulosic ethanol technology. Therefore, an ef’cient pretreatment is to be selected to decrease cellulose crystallinity and to remove lignin to ado essay much nothing the maximum extent, so that hydrolysis time as well as cellulase loading will be minimized. Surfactants modify the cellulose surface by adsorbing lignin onto surfactant and help me with depression thus the surfactant prevents the enzyme from unproductive binding with lignin and lowers enzyme loading (Eriksson et al, 2002). The sacchari’ed biomass is used for fermentation by several microorganisms.

But the industrial utilization of lignocelluloses for bioethanol production is hindered by the lack of ideal microor- ganisms which can ef’ciently ferment both pentose and hexose sugars (Talebnia et al, 2010). For a commercially viable ethanol production method, an ideal microorganism should have broad substrate utilization, high ethanol yield and productivity, should have the strategy case, ability to withstand high concentrations of ethanol and high temperature, should be tolerant to me with depression inhibitors present in hydrolysate and have cellulolytic activity. Genetically modi’ed or engineered microor- ganisms are thus used to achieve complete utilization of the sugars in magee questions the hydrolysate and better production bene’ts. The processes usually employed in the fermentation of ligno- cellulosic hydrolysate are simultaneous sacchari’cation and help depression fermentation (SSF) and separate hydrolysis and fermentation (SHF). Conventionally or traditionally the SHF process has been employed but SSF is superior for ethanol production since it can improve ethanol yields by removing end product inhibition and eliminate the need for separate reactors. It is also cost effective but difference in strategy case studies optimum temperature conditions of enzyme for hydrolysis and fermentation poses some limitations (Neves et al, 2007) . Help Me With? The higher ethanol yield coef’cient from SSF would be partially due to more conver- sion of xylose to xylitol under the SSF conditions (Buaban et al, 2010). A compar- ative study between the two processes (SHF and SSF) is presented in Table 3. Table 3. Comparison between the two main fermentation techniques.

Fermentation process Features and bertolt essay epische theater advantages Limitations. and fermentation ‘ Low costs. ‘ Higher ethanol yields due to removal of end product inhibition of sacchari’cation step. ‘ Reduces the number of reactors required Each step can be processed at its optimal operating conditions. ‘ Separate steps minimize interaction between the steps ‘ Difference in optimum temperature conditions of enzyme for hydrolysis and fermentation.

‘ End product inhibition minimizes the yield of ethanol. Chance of contamination due to help long period process. Separate hydrolysis and fermentation. Studies have shown that SSF is a better alternative to writing SHF. The slow xylose consumption during fermentation in SHF may be due to the presence of toxic compounds which inhibit the growth and fermentation activity of the microorganism. The drawback of SSF can be removed by help me with using thermo-tolerant micro- organisms like Kluyveromyces marxianus which has been developed to withstand the higher temperatures needed for enzymatic hydrolysis. Apart from SSF or SHF, the available alternatives are consoli- dated bioprocessing (CBP) and simultaneous sacchari’cation and co-fermentation (SSCF) (Cardona et al, 2009). In CBP, cellulase production, biomass hydrolysis and ethanol fermentation are all together carried out in a single reactor . The process is also known as direct microbial conversion (DMC). Mono- or co-culture of microorganisms is generally used to ferment cellulose directly to ethanol. Ado Essay Much Nothing? Application of CBP requires no capital investment for purchasing enzyme or its production. Bacteria such as Clostridium thermocellum and some fungi including Neurospora crassa, Fusarium oxysporum and Paecilomyces sp have shown this type of me with activity.

However, CBP is not an ef’cient process because of poor ethanol yields and long fermentation periods (3-12 days) (Szczodrak and Fiedurek, 1996). In SSCF the co-fermenting microorganisms need to be compatible in corporate strategy case essays terms of operating pH and temperature . A combination of Candida shehatae and Saccharomyces cerevisiae was reported as suitable for the SSCF process (Neves et al, 2007). Sequential fermentation with two different microor- ganisms in different time periods of the me with depression, fermentation process for better utilization of sugar has also been employed using S. cerevisiae in the ‘rst phase for hexose utilization and C. shehatae in the second phase for pentose utilization but ethanol yields achieved are not high (Sanchez and Cardona, 2008). Some native or wild type microorganisms used in the fermen- tation are S. cerevisiae, Escherichia coli, Zymomonas mobilis, Pachy- solen tannophilus, C. shehatae, Pichia stipitis, Candida brassicae, Mucor indicus etc. Among all the best known yeast and bacteria employed in ethanol production from article field proposal sport thesis track hexoses are S. cerevisiae and Z. mobilis respectively . But S. Me With? cerevisiae cannot utilize the main C-5 sugar e xylose e of the hydrolysate . Maniac Magee? Native organisms such as Pichia and Candida species can be used in place of S. cerevisiae and they can utilize xylose but their ethanol production rate is at least ‘vefold lower than that observed with S. cerevisiae . Different microorganisms have shown different yields of ethanol depending on their mono- mer utilization (Table 4). Table 4 Ethanol yields from various substrates by various microorganisms. Substrate Fermenting microbe Yield of ethanol Feature of the employed microorganism. Can ferment both glucose and xylose.

Utilizes xylose and glucose present. Adapted at increased concentration. Co-ferment glucose and xylose and. utilizes ethanol in absence of sugar. Ferment only glucose. Ferment glucose ‘rst and then. xylose from the me with depression, mixture. Sugar cane bagasse. Rice straw Pichia stipitis BCC15191. Recombinant Escherichia coli KO11.

Pichia stipitis NRRL Y-7124. Pichia stipitis A. Candida shehatae NCL-3501. Pichia stipitis NRRL Y-7124 0.29 0.02 g ethanol/g available fermentable sugars (glucose and xylose) after 24 h. 31.50 g of ethanol/L in 48 h equivalent to a theoretical maximum yield of article field thesis 91.5% 0.35 gp/gs Calculated as ‘nal ethanol. 0.41 gp/gs concentration divided by total sugar in me with depression the fermentation medium. 0.45 g/g and 0.5 g/g of sugar utilized produced from autohydrolysate by free and immobilized cells in 48 h.

0.37 g/g and 0.47 g/g of sugar utilized produced from acid hydrolysate by free and article sport thesis track immobilized cells in 48 h. Maximum ethanol production achieved 4 g/L. Maximum ethanol production achieved 6 g/L (78% of theoretical maximum) Can ferment both glucose and xylose. Utilizes xylose and help depression glucose present in hydrolysates. Adapted at increased concentration of brecht essay epische theater hydrolysate. Co-ferment glucose and xylose and. utilizes ethanol in absence of sugar. Ferment only glucose.

Ferment glucose ‘rst and then xylose from the mixture. Genetic engineering has been employed to develop the various aspects of me with fermentation from higher yield to better and wide substrate utilization to increased recovery rates. A number of genetically modi’ed microorganisms such as P. stipitis BCC15191 (Buaban et al, 2010) , P. stipitis NRRL Y-7124, recombinant E. coli KO11, C. shehatae NCL-3501 S. cerevisiae ATCC 26603 have been developed. Bertolt Brecht Epische? Strict anaerobic hemophilic bacteria such as Clostridium sp. and Thermoanaerobacter sp. have been proposed to explore the bene’ts of fermentation at elevated temperatures. Some other thermo-tolerant microorganisms developed are K. marxianus, Candida lusitanieae and Z. Help? mobilis (Bjerre et al, 1996). Lignocellulosic biomass has been projected to be one of the main resources for economically attractive bioethanol production.

Though theoretical ethanol yields from sugar and starch (g ethanol/ g substrate) are higher than from lignocellulose, these conventional sources are insuf’cient for worldwide bioethanol production. In that aspect agricultural wastes are renewable, less costly and nothing abundantly available in nature. Agricultural wastes do not demand separate land, water, and me with energy requirements. They do not have food value as well. For economically feasible bioethanol production, several hindrances are to be overcome. On Calamity Jane? These refer to me with the four major aspects which are feedstock, conversion technology, hydrolysis process, and fermentation con’guration. With regard to feedstock major obstacles are cost, supply, harvesting, and handling. As regards conversion technology the hindrances are biomass pro- cessing, proper and cost effective pretreatment technology to liberate cellulose and hemicellulose from their complex with lignin. In respect of the hydrolysis process the challenge is to achieve an ef’cient process for depolymerization of cellulose and hemi- cellulose to produce fermentable monomers with high concentra- tion. In this aspect enzymatic hydrolysis may be the writing formats, most potent alternative process for sacchari’cation of complex polymer. Several efforts have been made to depression reduce the bertolt, cost of cellulase enzyme to optimize the help depression, enzymatic hydrolysis process.

Finally, in case of fermentation con’guration, the challenges involved are xylose and glucose co-fermentation, and the use of recombinant microbial strains. In conclusion it may be said that to solve the technology bottlenecks of the conversion process, novel science and ef’cient technology are to be applied, so that bioethanol production from agricultural wastes may be successfully developed and optimized in the near future. 1. Buffiere P, Loisel D, Bernet N, Delgenes JP. Towards new indicators for the prediction of solid waste anaerobic digestion properties. Water Sci. Technol. 2006;53:233’241. 2. Grethelin HE. The effect of maniac magee pore size distribution on the rate of enzymatic hydrolysis of cellulosic substrates. Biotechnol.

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Carbohyd. Res. 2005;340:97’106. 30. Stenberg K, Tengborg C, Galbe M, Zacchi G. Optimisation of steam pretreatment of SO2-impregnated mixed softwoods for ethanol production. Magee Essay Questions? J. Chem. Technol.

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Chundawat SP, Venkatesh B, Dale BE. Effect of particle size based separation of milled corn stover on AFEX pretreatment and enzymatic digestibility. Biotechnol. Bioeng. 2007;96:219’231. 35. Essays Jane? Wyman CE.

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Enzyme Microb. Tech. 2006;39:1137’1144. 44. Sreenath HK, Koegel RG, Moldes AB, Jeffries TW, Straub RJ. Enzymic saccharification of help me with depression alfalfa fibre after liquid hot water pretreatment. Process Biochem. 1999;35:33’41. 45. Mosier N, Hendrickson R, Ho N, Sedlak M, Ladisch MR. Optimization of pH controlled liquid hot water pretreatment of corn stover.

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Palmqvist E, Hahn-H??gerdal B. Fermentation of lignocellulosic hydrolysates. II: Inhibitors and mechanisms of inhibition. Bioresource Technol. 2000;74:25’33. 48. Maniac Essay Questions? Sanchez G, Pilcher L, Roslander C, Modig T, Galbe M, Liden G. Help Me With Depression? Dilute-acid hydrolysis for fermentation of the Bolivian straw material Paja Brava. Strategy Case? Bioresource Technol. 2004;93:249’256. 49. Schell DJ, Farmer J, Newman M, McMillan JD. Dilute-sulfuric acid pretreatment of depression corn stover in pilot-scale reactor: Investigation of yields, kinetics, and enzymatic digestibilities of solids.

Appl. Biochem. Biotechnol. Article Field Sport Thesis Track? 2003;105:69’85. 50. Kassim EA, El-Shahed AS. Enzymatic and chemical hydrolysis of certain cellulosic materials. Help? Agr. Wastes. 1986;17:229’233. 51.

Xu Z, Wang Q, Jiang Z, Yang X-X, Ji Y. Enzymatic hydrolysis of field proposal sport thesis pretreated soybean straw. Biomass Bioenerg. 2007;31:162’167. 52. Curreli N, Fadda MB, Rescigno A, Rinaldi AC, Soddu G, Sollai F, Vaccargiu S, Sanjust E, Rinaldi A. Mild alkaline/oxidative pretreatment of wheat straw. Process Biochem. 1997;32:665’670. 53. Itoh H, Wada M, Honda Y, Kuwahara M, Watanabe T. Bioorganosolve pretreatments for simultaneous saccharification and fermentation of beech wood by ethanolysis and white rot fungi. J. Biotechnol. 2003;103:273’280.

54. Pan X, Gilkes N, Kadla J, Pye K, Saka S, Gregg D, Ehara K, Xie D, Lam D, Saddler J. Bioconversion of depression hybrid poplar to ethanol and co-products using an organosolv fractionation process: optimization of process yields. Biotechnol. Bioeng. Field Proposal Track? 2006;94:851’861. 55. Rolz C, de Arriola MC, Valladares J, de Cabrera S. Effects of some physical and chemical pretreatments on the composition and enzymatic hydrolysis and digestibility of me with lemon grass and citronella bagasse. Agr. Wastes. Essay Epische? 1986;18:145’161. 56.

Pan X, Arato C, Gilkes N, Gregg D, Mabee W, Pye K, Xiao Z, Zhang X, Saddler J. Biorefining of softwoods using ethanol organosolv pulping: Preliminary evaluation of process streams for manufacture of fuel-grade ethanol and co-products. Biotechnol. Bioeng. 2005;90:473’481. 57. Me With Depression? Schultz TP, McGinnis GD, Biermann CJ. Similarities and differences in pretreating woody biomass by steam explosion, wet oxidation, autohydrolysis, and rapid steam hydrolysis/continuous extraction. Theater? Proceedings of Annual Symposium on Energy from Biomass and Wastes; Lake Buena Vista, FL, USA.

1984. 58. Palonen H, Thomsen AB, Tenkanen M, Schmidt AS, Viikari L. Evaluation of wet oxidation pretreatment for enzymatic hydrolysis of softwood. Appl. Biochem. Biotechnol. 2004;117:1’17. 59. Varga E, Klinke HB, Reczey K, Thomsen AB.

High Solid Simultaneous Saccharification and Fermentation of Wet Oxidized Corn Stover to Ethanol. Biotechnol. Bioeng. 2004;88:567’574. 60. Garrote G, Dominguez H, Parajo JC. Hydrothermal processing of lignocellulosic materials. Holz Als Roh-und Werkst. Depression? 1999;57:191’202.

61. Schmidt A, Thomsen A. Optimization of wet oxidation pretreatment of wheat straw. Bioresource Technol. 1998;64:139’151. 62. Galbe M, Zacchi G. Field Proposal Track? A review of the production of ethanol from softwood. Appl. Microbiol. Depression? Biotechnol. 2002;59:618’628.

63. Paper Writing Formats? Azzam AM. Pretreatment of cane bagasse with alkaline hydrogen peroxide for enzymatic hydrolysis of help depression cellulose and bertolt theater ethanol fermentation. J. Environ. Me With Depression? Sci. Nothing? Heal. 1989;24:421’433. 64. Vidal PF, Molinier J. Ozonolysis of Lignin ‘ Improvement of in vitro digestibility of help poplar sawdust.

Biomass. 1988;16:1’17. 65. Neely WC. Factors affecting the pretreatment of biomass with gaseous ozone. Biotechnol. Bioeng. 1984;26:59’65. 66.

Taherzadeh MJ, Karimi K. Acid-based hydrolysis processes for ethanol from lignocellulosic materials: A review. BioResources. Ado Essay Nothing? 2007;2:472’499. 67. Jones J, Semrau K. Wood hydrolysis for ethanol production previous experience and the economics of selected processes.

Biomass. 1984;5:109’135. 68. Taherzadeh MJ, Karimi K. Enzymatic-based hydrolysis processes for me with depression, ethanol from lignocellulosic materials: A review. BioResources. Corporate Strategy Case Studies? 2007;2:707’738. 69.

Srilatha HR, Nand K, Babu KS, Madhukara K. Fungal pretreatment of orange processing wastes by solid-state fermentation for improved production of methane. Process Biochem. Me With Depression? 1995;30:327’331. 70. Dhouib A, Ellouz M, Aloui F, Sayadi S. Effect of bioaugmentation of activated sludge with white-rot fungi on olive mill wastewater detoxification. Lett. Ado Essay Much? Appl. Microbiol. Help? 2006;42:405’411.23. 71.

Stone JE, Scallan AM, Donefer E, Ahlgren E. In: Cellulases and much nothing their Applications. Hajny GJ, Reese ET, editors. American Chemical Society; Washington DC, USA: 1969. 72. Mohammad J. Taherzadeh , K. Karimi: Pretreatment of Lignocellulosic Wastes to Improve Ethanol and Biogas Production: A Review, Journal of help me with depression Molecular Sciences, Sep 2008. 73. Nibedita Sarkar, Sumanta Kumar Ghosh, Satarupa Bannerjee, Kaustav Aikat, Bioethanol production from agricultural wastes: An overview. 74. Uihlein A, Schbek L. Environmental impacts of a lignocellulosic feedstock biore’nery system: an assessment. Biomass and Bioenergy 2009;33:793-802. 75.

Ballesteros I, Negro MJ, Oliva JM, Cabanas A, Manzanares P, Ballesteros M. Ethanol production from bertolt brecht epische theater steam-explosion pretreated wheat straw. Applied Biochemistry and depression Biotechnology 2006;130:496-508. 76. Campbell CH, Laherrere JH. Ado Essay? The end of cheap oil. Scienti’c American; 1998:78-83.

77. Lynd LR, Wang MQ. A product e nonspeci’c framework for evaluating the potential of me with biomass-based products to displace fossil fuels. Essays? Journal of Industrial Ecology 2003;7:17-32. 78. Demirbas A. Bioethanol from cellulosic materials: a renewable motor fuel from biomass. Energy Sources 2005;27:327-33.

79. Me With? Lewis SM. Fermentation alcohol. In: Godfrey T, West S, editors. Industrial enzymology. 2nd ed. New York: Stockton Press; 1996. p. Ado Essay? 12-48.

80. [9] Taherzadeh MJ, Karimi K. Acid based hydrolysis processes for ethanol from lignocellulosic materials: a review. Bioresources 2007;2(3):472-99. 81. Chandra Prasad Pokhrel, Ram Kailash Prasad Yadav, Shoji Ohga-, Agricultural waste residues as potential sources of bioethanol , Scientific World, Vol. 6, No. 6, July 2008. 82. Help Me With Depression? Lewis SM.

Fermentation alcohol. In: Godfrey T, West S, editors. Industrial enzymology. 2nd ed. Ado Essay? New York: Stockton Press; 1996. Help Me With? p. 12-48. 83. Taherzadeh MJ, Karimi K. Acid based hydrolysis processes for ethanol from lignocellulosic materials: a review. Bioresources 2007;2(3):472-99.

84. Bjerre AB, Olesen AB, Fernqvist T. Pretreatment of wheat straw using combined wet oxidation and alkaline hydrolysis resulting in convertible cellulose and hemicellulose. Biotechnology and Bioengineering 1996;49: 568-77. 85. Talebnia F, Karakashev D, Angelidaki I. Production of bioethanol from wheat straw: an overview on pretreatment, hydrolysis and fermentation. Bio- resource Technology 2010;101(13):47, 44-53. 86. Much? Neves MA, Kimura T, Shimizu N, Nakajima M. State of the art and future trends of bioethanol production, dynamic biochemistry, process biotech- nology and molecular biology. Global Science Books; 2007:1-13.

87. Buaban B, Inoue H, Yano S, Tanapongpipat S, Ruanglek V, Champreda V, et al. Bioethanol production from ball milled bagasse using an on-site produced fungal enzyme cocktail and xylose-fermenting Pichia stipitis. Journal of Bioscience and me with Bioengineering 2010;110(1):18-25. 88. Lynd LR, van Zyl WH, Mcbride JE, Laser M. Consolidated bioprocessing of maniac magee cellulosic biomass: an update. Current Opinion in me with Biotechnology 2005;16(5):577-83. 89. Le Journal des ??nergies Renouvelables, 2013. 90.

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Chapter 6: Using PSFTP to help me with depression, transfer files securely. PSFTP, the PuTTY SFTP client, is a tool for on calamity transferring files securely between computers using an SSH connection. PSFTP differs from PSCP in the following ways: PSCP should work on me with depression, virtually every SSH server. PSFTP uses the new SFTP protocol, which is bertolt brecht essay epische, a feature of help, SSH-2 only. On Calamity. (PSCP will also use this protocol if it can, but there is an SSH-1 equivalent it can fall back to if it cannot.) PSFTP allows you to run an interactive file transfer session, much like the Windows ftp program. You can list the contents of me with, directories, browse around the file system, issue multiple get and put commands, and eventually log out. By contrast, PSCP is designed to do a single file transfer operation and immediately terminate. The usual way to start PSFTP is from essays on calamity jane a command prompt, much like PSCP.

To do this, it will need either to be on your PATH or in your current directory. To add the directory containing PSFTP to your PATH environment variable, type into the console window: Unlike PSCP, however, PSFTP has no complex command-line syntax; you just specify a host name and perhaps a user name: Alternatively, if you just type psftp on its own (or double-click the PSFTP icon in the Windows GUI), you will see the PSFTP prompt, and a message telling you PSFTP has not connected to any server: At this point you can type open or open to start a session.

PSFTP accepts all the general command line options supported by the PuTTY tools, except the ones which make no sense in help me with a file transfer utility. Article Sport. See section 3.8.3 for a description of these options. Help. (The ones not supported by PSFTP are clearly marked.) PSFTP also supports some of its own options. The following sections describe PSFTP's specific command-line options. 6.1.1 -b : specify a file containing batch commands. In normal operation, PSFTP is an corporate strategy case essays interactive program which displays a command line and help accepts commands from the keyboard. If you need to do automated tasks with PSFTP, you would probably prefer to specify a set of commands in on calamity advance and have them executed automatically. The -b option allows you to do this. Me With. You use it with a file name containing batch commands. For example, you might create a file called myscript.scr containing lines like this: and then you could run the script by typing.

When you run a batch script in this way, PSFTP will abort the maniac essay script if any command fails to complete successfully. Help Depression. To change this behaviour, you can add the -be option (section 6.1.3). PSFTP will terminate after it finishes executing the essays on calamity batch script. 6.1.2 -bc : display batch commands as they are run. The -bc option alters what PSFTP displays while processing a batch script specified with -b . With the -bc option, PSFTP will display prompts and commands just as if the commands had been typed at the keyboard.

So instead of seeing this: you might see this: 6.1.3 -be : continue batch processing on errors. When running a batch file, this additional option causes PSFTP to continue processing even if a command fails to complete successfully. You might want this to me with, happen if you wanted to delete a file and didn't care if it was already not present, for example. 6.1.4 -batch : avoid interactive prompts. If you use the -batch option, PSFTP will never give an interactive prompt while establishing the corporate strategy connection. If the server's host key is invalid, for example (see section 2.2), then the help connection will simply be abandoned instead of asking you what to do next. This may help PSFTP's behaviour when it is used in automated scripts: using -batch , if something goes wrong at connection time, the corporate strategy case batch job will fail rather than hang.

Once you have started your PSFTP session, you will see a psftp prompt. You can now type commands to me with, perform file-transfer functions. This section lists all the available commands. 6.2.1 General quoting rules for ado essay nothing PSFTP commands. Most PSFTP commands are considered by the PSFTP command interpreter as a sequence of words, separated by spaces. For example, the command ren oldfilename newfilename splits up into three words: ren (the command name), oldfilename (the name of the file to be renamed), and newfilename (the new name to help me with depression, give the bertolt epische file). Sometimes you will need to specify file names that contain spaces.

In order to do this, you can surround the file name with double quotes. Me With Depression. This works equally well for ado essay local file names and help remote file names: The double quotes themselves will not appear as part of the essay questions file names; they are removed by PSFTP and their only effect is to stop the depression spaces inside them from bertolt brecht acting as word separators. If you need to use a double quote (on some types of remote system, such as Unix, you are allowed to use double quotes in depression file names), you can do this by essays, doubling it. This works both inside and help depression outside double quotes. For example, this command. will take a file whose current name is this (with a double quote character at the beginning and the end) and rename it to a file whose name is a file with quotes in it . (The one exception to the PSFTP quoting rules is the ! command, which passes its command line straight to Windows without splitting it up into strategy case studies essays words at all. See section 6.2.19.) Several commands in PSFTP support ‘ wildcards’ to help me with depression, select multiple files. For local file specifications (such as the first argument to put ), wildcard rules for the local operating system are used. For instance, PSFTP running on Windows might require the field proposal thesis track use of me with depression, *.* where PSFTP on Unix would need * . For remote file specifications (such as the first argument to get ), PSFTP uses a standard wildcard syntax (similar to POSIX wildcards):

* matches any sequence of characters (including a zero-length sequence). ? matches exactly one character. [abc] matches exactly one character which can be a , b , or c . [a-z] matches any character in the range a to z . [^abc] matches a single character that is jane, not a , b , or c . Special cases: [-a] matches a literal hyphen ( - ) or a ; [^-a] matches all other characters. [a^] matches a literal caret ( ^ ) or a . (backslash) before any of the above characters (or itself) removes that character's special meaning. A leading period ( . ) on a filename is not treated specially, unlike in some Unix contexts; get * will fetch all files, whether or not they start with a leading period. 6.2.3 The open command: start a session. If you started PSFTP by double-clicking in the GUI, or just by typing psftp at the command line, you will need to depression, open a connection to on calamity jane, an SFTP server before you can issue any other commands (except help and me with depression quit ). To create a connection, type open , or if you need to specify a user name as well you can type open . Once you have issued this command, you will not be able to article proposal thesis track, issue it again, even if the me with depression command fails (for example, if you mistype the host name or the connection times out). So if the connection is not opened successfully, PSFTP will terminate immediately.

6.2.4 The quit command: end your session. When you have finished your session, type the command quit to close the connection, terminate PSFTP and return to the command line (or just close the article field sport PSFTP console window if you started it from the GUI). You can also use the bye and exit commands, which have exactly the same effect. 6.2.5 The close command: close your connection. If you just want to help me with, close the network connection but keep PSFTP running, you can use the close command. Proposal Sport Thesis Track. You can then use the open command to open a new connection. 6.2.6 The help command: get quick online help.

If you type help , PSFTP will give a short list of the available commands. If you type help with a command name - for depression example, help get - then PSFTP will give a short piece of help on that particular command. 6.2.7 The cd and much nothing pwd commands: changing the remote working directory. PSFTP maintains a notion of your ‘working directory’ on me with, the server. This is the default directory that other commands will operate on.

For example, if you type get filename.dat then PSFTP will look for filename.dat in your remote working directory on the server. To change your remote working directory, use the cd command. If you don't provide an argument, cd will return you to your home directory on the server (more precisely, the much nothing remote directory you were in at help me with, the start of the proposal sport track connection). To display your current remote working directory, type pwd . 6.2.8 The lcd and help lpwd commands: changing the local working directory. As well as having a working directory on the remote server, PSFTP also has a working directory on corporate case studies essays, your local machine (just like any other Windows process). This is the default local directory that other commands will operate on. For example, if you type get filename.dat then PSFTP will save the help depression resulting file as filename.dat in your local working directory. To change your local working directory, use the lcd command. To display your current local working directory, type lpwd . 6.2.9 The get command: fetch a file from the server. To download a file from the server and store it on your local PC, you use the get command. In its simplest form, you just use this with a file name:

If you want to store the file locally under a different name, specify the local file name after the remote one: This will fetch the jane file on the server called myfile.dat , but will save it to your local machine under the name newname.dat . To fetch an help entire directory recursively, you can use the -r option: (If you want to fetch a file whose name starts with a hyphen, you may have to on calamity jane, use the help me with -- special argument, which stops get from interpreting anything as a switch after it. For example, ‘ get -- -silly-name- ’.) 6.2.10 The put command: send a file to the server. To upload a file to magee essay, the server from your local PC, you use the put command.

In its simplest form, you just use this with a file name: If you want to store the file remotely under a different name, specify the help depression remote file name after the local one: This will send the local file called myfile.dat , but will store it on the server under the name newname.dat . To send an entire directory recursively, you can use the -r option: (If you want to send a file whose name starts with a hyphen, you may have to use the -- special argument, which stops put from interpreting anything as a switch after it. For example, ‘ put -- -silly-name- ’.) 6.2.11 The mget and on calamity mput commands: fetch or send multiple files. mget works almost exactly like get , except that it allows you to specify more than one file to fetch at help me with, once. Bertolt Brecht Essay Epische Theater. You can do this in help me with two ways:

by giving two or more explicit file names (‘ mget file1.txt file2.txt ’) by using a wildcard (‘ mget *.txt ’). Every argument to mget is treated as the name of essays on calamity jane, a file to depression, fetch (unlike get , which will interpret at most one argument like that, and a second argument will be treated as an alternative name under which to store the retrieved file), or a wildcard expression matching more than one file. The -r and -- options from get are also available with mget . mput is similar to put , with the writing same differences. 6.2.12 The reget and reput commands: resuming file transfers. If a file transfer fails half way through, and you end up with half the depression file stored on college paper, your disk, you can resume the file transfer using the help depression reget and reput commands. These work exactly like the get and put commands, but they check for maniac questions the presence of the help me with depression half-written destination file and start transferring from where the last attempt left off. The syntax of reget and reput is exactly the same as the syntax of get and put : These commands are intended mainly for resuming interrupted transfers. Article Field Sport Thesis Track. They assume that the remote file or directory structure has not changed in any way; if there have been changes, you may end up with corrupted files.

In particular, the depression -r option will not pick up changes to files or directories already transferred in full. 6.2.13 The dir command: list remote files. To list the ado essay much nothing files in help me with your remote working directory, just type dir . You can also list the contents of a different directory by typing dir followed by the directory name: And you can list a subset of the contents of a directory by providing a wildcard: The ls command works exactly the same way as dir . 6.2.14 The chmod command: change permissions on remote files. PSFTP allows you to modify the file permissions on files and directories on the server. You do this using the chmod command, which works very much like the Unix chmod command.

The basic syntax is chmod modes file , where modes represents a modification to the file permissions, and file is the filename to modify. You can specify multiple files or wildcards. Essays On Calamity. For example: The modes parameter can be a set of help, octal digits in maniac magee essay the Unix style. (If you don't know what this means, you probably don't want to help me with depression, be using it!) Alternatively, it can be a list of permission modifications, separated by commas. Each modification consists of: The people affected by the modification. This can be u (the owning user), g (members of the owning group), or o (everybody else - ‘others’), or some combination of those.

It can also be a (‘all’) to affect everybody at once. A + or - sign, indicating whether permissions are to on calamity, be added or removed. Me With. The actual permissions being added or removed. These can be r (permission to maniac magee essay questions, read the file), w (permission to write to help me with, the file), and x (permission to execute the magee questions file, or in the case of a directory, permission to me with, access files within the directory). So the above examples would do: The first example: go-rwx removes read, write and execute permissions for article field thesis track members of the owning group and everybody else (so the only permissions left are the ones for the file owner). Help Depression. u+w adds write permission for the file owner. The second example: a+r adds read permission for everybody to all files and directories starting with ‘public’. In addition to all this, there are a few extra special cases for Unix systems. On non-Unix systems these are unlikely to be useful: You can specify u+s and u-s to add or remove the Unix set-user-ID bit.

This is typically only useful for special purposes; refer to on calamity, your Unix documentation if you're not sure about it. You can specify g+s and me with depression g-s to add or remove the Unix set-group-ID bit. On a file, this works similarly to magee questions, the set-user-ID bit (see your Unix documentation again); on help me with depression, a directory it ensures that files created in formats the directory are accessible by members of the group that owns the help me with directory. You can specify +t and bertolt theater -t to add or remove the Unix ‘ sticky bit’. When applied to a directory, this means that the owner of help depression, a file in that directory can delete the file (whereas normally only the college writing formats owner of the me with directory would be allowed to). 6.2.15 The del command: delete remote files. To delete a file on the server, type del and then the filename or filenames: Files will be deleted without further prompting, even if multiple files are specified. del will only delete files. You cannot use it to delete directories; use rmdir for that. The rm command works exactly the same way as del . 6.2.16 The mkdir command: create remote directories.

To create a directory on magee essay questions, the server, type mkdir and me with depression then the bertolt theater directory name: You can specify multiple directories to help depression, create at once: 6.2.17 The rmdir command: remove remote directories. To remove a directory on the server, type rmdir and then the directory name or names: Directories will be deleted without further prompting, even if multiple directories are specified. Most SFTP servers will probably refuse to remove a directory if the directory has anything in it, so you will need to magee essay, delete the contents first. 6.2.18 The mv command: move and rename remote files.

To rename a single file on me with, the server, type mv , then the current file name, and then the new file name: You can also move the file into a different directory and change the name: To move one or more files into an existing subdirectory, specify the strategy essays files (using wildcards if desired), and then the destination directory: The rename and ren commands work exactly the same way as mv . 6.2.19 The ! command: run a local Windows command. You can run local Windows commands using the ! command. This is the only PSFTP command that is not subject to the command quoting rules given in section 6.2.1. If any command line begins with the help me with ! character, then the rest of the line will be passed straight to questions, Windows without further translation. For example, if you want to help, move an existing copy of proposal track, a file out help, of the way before downloading an ado essay updated version, you might type: using the Windows ren command to rename files on your local PC.

6.3 Using public key authentication with PSFTP. Like PuTTY, PSFTP can authenticate using a public key instead of a password. There are three ways you can do this. Firstly, PSFTP can use PuTTY saved sessions in place of hostnames. So you might do this: Run PuTTY, and create a PuTTY saved session (see section 4.1.2) which specifies your private key file (see section 4.20.7).

You will probably also want to me with, specify a username to log in corporate case essays as (see section 4.14.1). In PSFTP, you can now use the name of the session instead of a hostname: type psftp sessionname , where sessionname is replaced by the name of your saved session. Secondly, you can supply the me with name of maniac essay, a private key file on the command line, with the -i option. See section for more information. Thirdly, PSFTP will attempt to authenticate using Pageant if Pageant is help depression, running (see chapter 9). Ado Essay. So you would do this:

Ensure Pageant is running, and has your private key stored in it. Specify a user and help me with host name to PSFTP as normal. PSFTP will automatically detect Pageant and try to use the keys within it. For more general information on public-key authentication, see chapter 8. If you want to corporate studies essays, provide feedback on this manual or on me with depression, the PuTTY tools themselves, see the Feedback page.